Ying Z Pigli
Overview
Explore the profile of Ying Z Pigli including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
221
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0
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Recent Articles
1.
Hossain A, Pigli Y, Baca C, Heissel S, Thomas A, Libis V, et al.
Nature
. 2024 Apr;
629(8011):410-416.
PMID: 38632404
Bacteria have adapted to phage predation by evolving a vast assortment of defence systems. Although anti-phage immunity genes can be identified using bioinformatic tools, the discovery of novel systems is...
2.
Mir-Sanchis I, Roman C, Misiura A, Pigli Y, Boyle-Vavra S, Rice P
Nat Struct Mol Biol
. 2016 Aug;
23(10):891-898.
PMID: 27571176
Methicillin-resistant Staphylococcus aureus (MRSA) is a public-health threat worldwide. Although the mobile genomic island responsible for this phenotype, staphylococcal cassette chromosome (SCC), has been thought to be nonreplicative, we predicted...
3.
Misiura A, Pigli Y, Boyle-Vavra S, Daum R, Boocock M, Rice P
Mol Microbiol
. 2013 May;
88(6):1218-29.
PMID: 23651464
Methicillin-resistant Staphylococcus aureus (MRSA) emerged via acquisition of a mobile element, staphylococcal cassette chromosome mec (SCCmec). Integration and excision of SCCmec is mediated by an unusual site-specific recombination system. Most...
4.
Montano S, Pigli Y, Rice P
Nature
. 2012 Nov;
491(7424):413-7.
PMID: 23135398
Studies of bacteriophage Mu transposition paved the way for understanding retroviral integration and V(D)J recombination as well as many other DNA transposition reactions. Here we report the structure of the...
5.
Zhang A, Pigli Y, Rice P
Nature
. 2010 Aug;
466(7308):883-6.
PMID: 20703307
The eubacterial SOS system is a paradigm of cellular DNA damage and repair, and its activation can contribute to antibiotic resistance. Under normal conditions, LexA represses the transcription of many...
6.
Grigorescu A, Vissers J, Ristic D, Pigli Y, Lynch T, Wyman C, et al.
Nucleic Acids Res
. 2008 Dec;
37(2):557-67.
PMID: 19066203
Rad51 is the central catalyst of homologous recombination in eukaryotes and is thus critical for maintaining genomic integrity. Recent crystal structures of filaments formed by Rad51 and the closely related...
7.
Peng X, Pigli Y, Rice P, Greenberg M
J Am Chem Soc
. 2008 Sep;
130(39):12890-1.
PMID: 18778053
Oxidative DNA damage is important in aging and a variety of diseases. Significant advances have been made in our understanding of the chemistry of radical mediated DNA damage. These studies...