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Ying V Liu

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Recent Articles
1.
Wang J, Nnoromele P, Liu Y, Johnston Jr R, Singh M
Prog Retin Eye Res . 2024 Nov; 104:101317. PMID: 39551387
Photoreceptor transplantation is a potential therapeutic strategy for degenerative retinal diseases. Studies on mechanisms contributing to retinal regeneration and vision repair identified cellular components transfer (CCT) as playing a role,...
2.
Nnoromele P, Adams M, Pan A, Liu Y, Wang J, Singh M
Curr Opin Genet Dev . 2024 Nov; 89:102277. PMID: 39549608
The transplantation of human organoid-derived retinal cells is being studied as a potentially viable strategy to treat vision loss due to retinal degeneration. Experiments in animal models have demonstrated the...
3.
Bellingrath J, Li K, Aziz K, Izzi J, Liu Y, Singh M
Front Ophthalmol (Lausanne) . 2024 Sep; 4:1377098. PMID: 39253560
Aim: Retinal cell therapy modalities, in the category of advanced therapy medicinal products (ATMPs), are being developed to target several retinal diseases. Testing in large animal models (LAMs) is a...
4.
Liu Y, Li K, Li Z, Lu Y, McNally M, Esposito E, et al.
J Vis Exp . 2024 Feb; (203). PMID: 38345250
Transplantation of photoreceptor cells and retinal pigment epithelial (RPE) cells provide a potential therapy for retinal degeneration diseases. Subretinal transplantation of therapeutic donor cells into mouse recipients is challenging due...
5.
Liu Y, Santiago C, Sogunro A, Konar G, Hu M, McNally M, et al.
Stem Cell Reports . 2023 May; 18(5):1138-1154. PMID: 37163980
Human retinal organoid transplantation could potentially be a treatment for degenerative retinal diseases. How the recipient retina regulates the survival, maturation, and proliferation of transplanted organoid cells is unknown. We...
6.
Liu Y, Konar G, Aziz K, Tun S, Hua C, Tan B, et al.
Invest Ophthalmol Vis Sci . 2021 Oct; 62(13):8. PMID: 34643661
Purpose: Cell-based therapy development for geographic atrophy (GA) in age-related macular degeneration (AMD) is hampered by the paucity of models of localized photoreceptor and retinal pigment epithelium (RPE) degeneration. We...
7.
Liu Y, Teng D, Konar G, Agakishiev D, Biggs-Garcia A, Harris-Bookman S, et al.
Exp Eye Res . 2021 Aug; 210:108715. PMID: 34343570
Objectives: Cone photoreceptor transplantation is a potential treatment for macular diseases. The optimal conditions for cone transplantation are poorly understood, partly because of the scarcity of cones in donor mice....
8.
Liu Y, Sodhi S, Xue G, Teng D, Agakishiev D, McNally M, et al.
Transl Vis Sci Technol . 2020 Aug; 9(7):5. PMID: 32832212
Purpose: Short-term improvements in retinal anatomy are known to occur in preclinical models of photoreceptor transplantation. However, correlative changes over the long term are poorly understood. We aimed to develop...