Yin-Xia Chen
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Explore the profile of Yin-Xia Chen including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
393
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Recent Articles
1.
Wang B, Zhao W, Chen Y, Cao X, Yang Y, Zhang Y, et al.
J Med Case Rep
. 2022 Dec;
16(1):459.
PMID: 36496425
Background: Multiple myeloma remains incurable despite treatment advancements over the last 20 years. LCAR-B38M Cells in Treating Relapsed/Refractory Multiple Myeloma was a phase 1, first-in-human, investigator-initiated study in relapsed/refractory multiple...
2.
Zhao W, Wang B, Chen L, Fu W, Xu J, Liu J, et al.
J Hematol Oncol
. 2022 Jul;
15(1):86.
PMID: 35794616
Background: LCAR-B38M is a chimeric antigen receptor T cell product with two binding domains targeting B cell maturation antigen. Our previous reports showed a remarkable efficacy of LCAR-B38M in patients...
3.
Lei B, Zhang W, He A, Chen Y, Cao X, Zhang P, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2019 Oct;
27(5):1463-1468.
PMID: 31607299
Objective: To investigate the transcriptional regulation of transcription factor MZF-1 on acute monocytic leukemia-related gene MLAA-34. Methods: The effect of MZF-1 on the transcriptional activity of MLAA-34 gene promoter was...
4.
Lei B, Zhang W, He A, Chen Y, Cao X, Zhao W, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2019 Jun;
27(3):641-645.
PMID: 31204911
Objective: To clone the promoter sequence of acute monocytic leukemia new antigen gene.MLAA-34 and identify its promoter core region. Methods: The full-length fragment of MLAA-34 gene promoter region was amplified...
5.
Zhao W, Liu J, Wang B, Chen Y, Cao X, Yang Y, et al.
J Hematol Oncol
. 2018 Dec;
11(1):141.
PMID: 30572922
Background: Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell...
6.
Lei B, Zhang W, Chen Y, He A, Cao X, Zhao W, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2018 Feb;
26(1):97-104.
PMID: 29397825
Objective: To investigate the correlation of all exone mutation in MLAA-34 gene with chemotherapeutic efficacy for leukemia. Methods: The expression level of MLAA-34 gene in 40 patients with AML-M5 and...
7.
Ma X, Xu Y, Wang J, Zhang W, Chen Y, Cao X, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2016 Aug;
24(4):1044-50.
PMID: 27531772
Objective: To analyze the clinical characteristics and prognostic factors of patients with non-Hodgkin's lymphoma (NHL) in single center of the Northwest area in China for 10 years, so as to...
8.
Wang F, Zhang W, He A, Cao X, Chen Y, Zhao W, et al.
Leuk Res
. 2016 Aug;
48:57-61.
PMID: 27497340
As sensitization of leukemia cells with granulocyte colony-stimulating factor (G-CSF) can enhance the cytotoxicity of chemotherapy in myeloid malignancies, a pilot study was conducted in order to evaluate the effect...
9.
Xu Y, Wang J, Yang N, Bai J, Zhang P, Gu L, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2016 May;
24(2):405-10.
PMID: 27151000
Objective: To explore the effectiveness and safety of combined chemotherapy with pegasparaginase (PEG-Asp) for treatment of patients with acute lymphoblastic leukemia (ALL) and T cell non-Hodgkin's lymphoma (T-NHL) patients. Methods:...
10.
Zhang P, Zhao X, Zhang W, Zhang W, Chen Y
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2016 May;
24(2):363-8.
PMID: 27150993
Objective: To study the antiapoptotic effect of leukemia-associated gene MLAA-34 in HeLa cells. Methods: The MLAA-34 recombinant lentiviral expression vector was constructed, and the stably transfected HeLa cell line with...