Yijie Qu

Photodynamic therapy has established itself as a clinical treatment for certain superficial cancers by converting oxygen into cytotoxic singlet oxygen to eradicate cancer cells. Porphyrin-based nanoscale metal-organic frameworks have emerged...

Porphyrin's excellent biocompatibility and modifiability make it a widely studied photoactive material. However, its large π-bond conjugated structure leads to aggregation and precipitation in physiological solutions, limiting the biomedical applications...

Porphyrins-based nanoscale metal-organic frameworks (nMOFs) has been widely utilized to kills tumor cells by generating cytotoxic reactive oxygen species (ROS). However, porphyrin based nMOFs (por-nMOFs) still face challenges such as...

Photodynamic therapy and ferroptosis induction have risen as vanguard oncological interventions, distinguished by their precision and ability to target vulnerabilities in cancer cells. Photodynamic therapy's non-invasive profile and selective cytotoxicity...

A conjugated polymer, P4TTD-DPP, based on tetra-fused isoindigo--diketopyrrolopyrrole, has been synthesized as a photothermal therapeutic nanotransducer within the near-infrared-II (NIR-II) window. P4TTD-DPP exhibits a notable mass extinction coefficient of 62.8...

Despite that deep learning has achieved state-of-the-art performance for automatic medical image segmentation, it often requires a large amount of pixel-level manual annotations for training. Obtaining these high-quality annotations is...

Background And Objective: Open-source deep learning toolkits are one of the driving forces for developing medical image segmentation models that are essential for computer-assisted diagnosis and treatment procedures. Existing toolkits...

Background: Delineation of Organs-at-Risks (OARs) is an important step in radiotherapy treatment planning. As manual delineation is time-consuming, labor-intensive and affected by inter- and intra-observer variability, a robust and efficient...