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Yihenew Simegniew Birhan

Explore the profile of Yihenew Simegniew Birhan including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 144
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Recent Articles
11.
Birhan Y, Tsai H
J Mater Chem B . 2021 Aug; 9(34):6770-6801. PMID: 34350452
Selenium is capable of forming a dynamic covalent bond with itself and other elements and can undergo metathesis and regeneration reactions under optimum conditions. Its dynamic nature endows selenium-containing polymers...
12.
Mekonnen T, Andrgie A, Darge H, Birhan Y, Hanurry E, Chou H, et al.
Pharmaceutics . 2020 Nov; 12(11). PMID: 33182410
Maximizing the antitumor efficacy of doxorubicin (DOX) with a new drug delivery strategy is always desired in the field of biomedical science. Because the clinical applications of DOX in the...
13.
Andrgie A, Darge H, Mekonnen T, Birhan Y, Hanurry E, Chou H, et al.
Polymers (Basel) . 2020 Nov; 12(11). PMID: 33172099
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their ability to form a highly moist environment which accelerates cell migration and tissue regeneration for prompt wound...
14.
Birhan Y, Darge H, Hanurry E, Andrgie A, Mekonnen T, Chou H, et al.
Pharmaceutics . 2020 Jun; 12(6). PMID: 32585885
Polymeric micelles (PMs) have been used to improve the poor aqueous solubility, slow absorption and non-selective biodistribution of chemotherapeutic agents (CAs), albeit, they suffer from disassembly and premature release of...
15.
Hanurry E, Mekonnen T, Andrgie A, Darge H, Birhan Y, Hsu W, et al.
Pharmaceutics . 2020 May; 12(5). PMID: 32403321
Biotin receptors are overexpressed by various types of solid cancer cells and play a significant role in tumor metabolism, growth, and metastasis. Thus, targeting the biotin receptors on tumor cells...
16.
Andrgie A, Birhan Y, Mekonnen T, Hanurry E, Darge H, Lee R, et al.
Polymers (Basel) . 2020 Jan; 12(1). PMID: 31892144
Polymeric prodrug-based delivery systems have been extensively studied to find a better solution for the limitations of a single drug and to improve the therapeutic and pharmacodynamics properties of chemotherapeutic...
17.
Hanurry E, Hsu W, Darge H, Birhan Y, Mekonnen T, Andrgie A, et al.
Mater Sci Eng C Mater Biol Appl . 2019 Nov; 106:110245. PMID: 31753357
The recent discovery of small interfering RNAs (siRNAs) has opened new avenues for designing personalized treatment options for various diseases. However, the therapeutic application of siRNAs has been confronted with...
18.
Darge H, Andrgie A, Hanurry E, Birhan Y, Mekonnen T, Chou H, et al.
Int J Pharm . 2019 Nov; 572:118799. PMID: 31678386
In a malignant tumor, overexpression of pro-angiogenic factors like vascular endothelial growth factor (VEGF) provokes the production of pathologic vascular networks characterized by leaky, chaotically organized, immature, thin-walled, and ill-perfused....
19.
Mekonnen T, Birhan Y, Andrgie A, Hanurry E, Darge H, Chou H, et al.
Colloids Surf B Biointerfaces . 2019 Oct; 184:110531. PMID: 31590053
Iron oxide-based magnetic resonance imaging (MRI) contrast agents have negative contrast limitations in cancer diagnosis. Gadolinium (Gd)-based contrast agents show toxicity. To overcome these limitations, Gd-doped ferrite (Gd:FeO (GdIO) nanoparticles...
20.
Birhan Y, Hailemeskel B, Mekonnen T, Hanurry E, Darge H, Andrgie A, et al.
Int J Pharm . 2019 Jul; 567:118486. PMID: 31260783
Stimuli-responsive polymeric nanostructures have emerged as potential drug carriers for cancer therapy. Herein, we synthesized redox-responsive diselenide bond containing amphiphilic polymer, Bi(mPEG-PLGA)-Se from mPEG-PLGA and 3,3'-diselanediyldipropanoic acid (DSeDPA) using DCC/DMAP...