Yifeng Chai
Overview
Explore the profile of Yifeng Chai including associated specialties, affiliations and a list of published articles.
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172
Citations
1509
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Recent Articles
1.
Chen C, Chai X, Gu Y, Wang C, Yuan Y, Chai Y, et al.
J Chromatogr A
. 2025 Feb;
1746:465775.
PMID: 39970684
Membrane receptor affinity chromatography is a practical strategy for screening compounds targeting membrane receptors and determining their binding affinity. The key of these methods is to create a biomimetic cell...
2.
Li Y, Gu Y, Shi Y, Zhang B, Pan S, Chai Y, et al.
J Pharm Biomed Anal
. 2024 Dec;
255():116595.
PMID: 39631165
Saposhnikovia divaricata (SD) is a traditional Chinese medicine (TCM) which has been commonly used for the treatment of rheumatoid arthritis (RA). However, its active components and mechanism of anti-RA are...
3.
Ma X, He Y, Lv D, Chen X, Hong Z, Chai Y, et al.
J Pharm Biomed Anal
. 2024 Oct;
252:116508.
PMID: 39426275
Metabolomics intends to maximize the quantity of available metabolites for the global metabolome, which largely depends on sample pretreatment protocols. However, there are few studies that comprehensively examined the effects...
4.
Wang C, Gu Y, Chen C, Li Y, Li L, Chai Y, et al.
Anal Chem
. 2024 Jun;
96(28):11479-11487.
PMID: 38943570
Accurate orientations and stable conformations of membrane receptor immobilization are particularly imperative for accurate drug screening and ligand-protein affinity analysis. However, there remain challenges associated with (1) traditional recombination, purification,...
5.
Lv D, Wang D, Li D, Guo D, Qi M, Zhang Y, et al.
Biomed Chromatogr
. 2024 Jun;
38(8):e5925.
PMID: 38837800
The rapid and accurate detection of illegal adulteration of chemical drugs into dietary supplements is a big challenge in the food chemistry field. Detection of compounds without a standard reference...
6.
Zhang Y, Wang D, Wang X, Ma H, Liu Y, Hong Z, et al.
J Pharm Biomed Anal
. 2024 Apr;
245:116142.
PMID: 38631070
Traditional Chinese Medicine (TCM) is a supremely valuable resource for the development of drug discovery. Few methods are capable of hunting for potential molecule ligands from TCM towards more than...
7.
Fang J, Shen S, Wang H, He Y, Chao L, Cao Y, et al.
Talanta
. 2024 Mar;
274:125987.
PMID: 38552478
Multidrug resistance (MDR) is a dominant challenge in cancer chemotherapy failure. The over-expression of breast cancer resistance protein (BCRP) in tumorous cells, along with its extensive substrate profile, is a...
8.
Fang J, He Y, Cao Y, Shi Y, Wang H, Hong Z, et al.
ACS Chem Neurosci
. 2023 Jan;
14(4):766-772.
PMID: 36704945
Bunge () is a traditional Chinese medicine that has been widely used in the treatment of various central nervous system (CNS) diseases. However, the mechanism of active components of crossing...
9.
Qi M, Lv D, Zhang Y, Wang D, Chen X, Zhu Z, et al.
J Pharm Anal
. 2023 Jan;
12(6):929-936.
PMID: 36605571
Therapeutic drug monitoring (TDM) has played an important role in clinical medicine for precise dosing. Currently, chromatographic technology and immunoassay detection are widely used in TDM and have met most...
10.
Dai J, He Y, Fang J, Wang H, Chao L, Zhao L, et al.
Molecules
. 2022 Dec;
27(23).
PMID: 36500651
The efficacy and pharmacokinetics of the biologically active components in (AR) would be affected by the interaction of P-glycoprotein(P-gp) and effective components in AR. However, little is known about the...