Yi-Zong Lee
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Explore the profile of Yi-Zong Lee including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
95
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Recent Articles
1.
Lee Y, Zhang Y, Newby M, Ward G, Gomes K, Auclair S, et al.
bioRxiv
. 2025 Mar;
PMID: 40060701
One-sentence Summary: Filovirus glycoproteins and nanoparticles were rationally designed and characterized and to aid filovirus vaccine development.
2.
Wu C, Lee Y, Hu I, Chiu L, Ding W, Wang J, et al.
Biomol NMR Assign
. 2025 Feb;
PMID: 39934620
Dopamine N-acetyltransferase (Dat), belonging to the GCN5-related N-acetyltransferase (GNAT) superfamily, is an arylalkylamine N-acetyltransferase (AANAT) that is involved in insects neurotransmitter inactivation and the development of insect cuticle sclerotization. By...
3.
Lee Y, Han J, Zhang Y, Ward G, Gomes K, Auclair S, et al.
Nat Commun
. 2024 Nov;
15(1):9939.
PMID: 39550381
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) cause human respiratory diseases and are major targets for vaccine development. In this study, we design uncleaved prefusion-closed (UFC) trimers for the...
4.
Zhang Y, Gomes K, Lee Y, Ward G, Xie B, Auclair S, et al.
Vaccines (Basel)
. 2024 Sep;
12(9).
PMID: 39340007
The development of an effective and broadly protective influenza vaccine against circulating and emerging strains remains elusive. In this study, we evaluated a potentially universal influenza vaccine based on single-component...
5.
Lee Y, Han J, Zhang Y, Ward G, Gomes K, Auclair S, et al.
bioRxiv
. 2024 Mar;
PMID: 38496645
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) cause human respiratory diseases and are major targets for vaccine development. In this study, we designed uncleaved prefusion-closed (UFC) trimers for the...
6.
Gomes K, Zhang Y, Lee Y, Eldad M, Lim A, Ward G, et al.
ACS Nano
. 2023 Nov;
17(23):23545-23567.
PMID: 37988765
The development of a cross-protective pan-influenza A vaccine remains a significant challenge. In this study, we designed and evaluated single-component self-assembling protein nanoparticles (SApNPs) presenting the conserved extracellular domain of...
7.
Zhang Y, Paynter J, Antanasijevic A, Allen J, Eldad M, Lee Y, et al.
Nat Commun
. 2023 Apr;
14(1):1985.
PMID: 37031217
Uncleaved prefusion-optimized (UFO) design can stabilize diverse HIV-1 envelope glycoproteins (Envs). Single-component, self-assembling protein nanoparticles (1c-SApNP) can display 8 or 20 native-like Env trimers as vaccine candidates. We characterize the...
8.
Liu Y, Chuang C, Lee Y, Lee E, Lo C, Wu C, et al.
Biochemistry
. 2023 Jan;
62(3):722-734.
PMID: 36626574
Chemokine CXCL4L1, a homologue of CXCL4, is a more potent antiangiogenic ligand. Its structural property is correlated with the downstream receptor binding. The two chemokines execute their functions by binding...
9.
Wu C, Chih Y, Hsieh H, Peng K, Lee Y, Yip B, et al.
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740373
Cecropins are a family of antimicrobial peptides (AMPs) that are widely found in the innate immune system of Cecropia moths. Cecropins exhibit a broad spectrum of antimicrobial and anticancer activities....
10.
Chen Y, Hsiao N, Lee Y, Huang S, Chang C, Tsai J, et al.
Int J Mol Sci
. 2021 Oct;
22(20).
PMID: 34681803
A neuropeptide (Sco-CHH-L), belonging to the crustacean hyperglycemic hormone (CHH) superfamily and preferentially expressed in the pericardial organs (POs) of the mud crab , was functionally and structurally studied. Its...