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Yi-Heng Hsieh

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Recent Articles
1.
Lin T, Huang C, Lin K, Hsieh Y, Chen S, Lin Y, et al.
Antioxidants (Basel) . 2024 Nov; 13(11). PMID: 39594520
The major pathological characteristics of Alzheimer's disease (AD) include senile plaques and neurofibrillary tangles (NFTs), which are mainly composed of aggregated amyloid-beta (Aβ) peptide and hyperphosphorylated tau protein, respectively. The...
2.
Wu M, Chao A, Hsieh Y, Lien Y, Lin Y, Yang D
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273571
Amyloid-beta peptide (Aβ) is a neurotoxic constituent of senile plaques in the brains of Alzheimer's disease (AD) patients. The detailed mechanisms by which protein kinase C-delta (PKCδ) contributes to Aβ...
3.
Chen S, Yang J, Hsieh Y, Lin T, Lin Y, Chao A, et al.
Biomedicines . 2021 Oct; 9(10). PMID: 34680426
Alzheimer's disease (AD) is the most common age-related neurodegenerative disease. It presents with progressive memory loss, worsens cognitive functions to the point of disability, and causes heavy socioeconomic burdens to...
4.
Hsieh Y, Chao A, Lin Y, Chen S, Yang D
Free Radic Biol Med . 2021 Apr; 169:36-61. PMID: 33852931
Accumulation of senile plaques mainly composed of neurotoxic amyloid-beta peptide (Aβ) is a pathological hallmark of Alzheimer's disease (AD). Sestrin2 inducible by various types of stressors is known to promote...