Yi-Chi M Kong
Overview
Explore the profile of Yi-Chi M Kong including associated specialties, affiliations and a list of published articles.
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28
Citations
439
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Recent Articles
1.
Kong Y, Flynn J
Front Immunol
. 2014 Jun;
5:206.
PMID: 24904570
To improve the efficacy of immunotherapy for cancer and autoimmune diseases, recent ongoing and completed clinical trials have focused on specific targets to redirect the immune network toward eradicating a...
2.
Kari S, Flynn J, Zulfiqar M, Snower D, Elliott B, Kong Y
Thyroid
. 2013 Jun;
23(12):1590-9.
PMID: 23777580
Background: Immunotherapeutic modalities to bolster tumor immunity by targeting specific sites of the immune network often result in immune dysregulation with adverse autoimmune sequelae. To understand the relative risk for...
3.
Kong Y, Brown N, Flynn J, McCormick D, Brusic V, Morris G, et al.
J Autoimmun
. 2011 Jun;
37(2):63-70.
PMID: 21683551
Thyroglobulin (Tg), a homodimer of 660 kD comprising 2748 amino acids, is the largest autoantigen known. The prevalence of autoimmune thyroid disease, including Hashimoto's thyroiditis and Graves' disease, has provided...
4.
Venuprasad K, Poojary K, Kong Y, Farrar M
Am J Pathol
. 2010 Jun;
177(2):525-31.
PMID: 20566752
Allergic diseases and asthma are caused by dysregulated Th2-type immune responses, which drive disease development in susceptible individuals. Immune tolerance to allergens prevents inflammatory symptoms in the respiratory mucosa and...
5.
Kong Y, Wei W, Tomer Y
Ann N Y Acad Sci
. 2010 Feb;
1183:222-36.
PMID: 20146718
Rapid advances in our understanding of the immune network have led to treatment modalities for malignancies and autoimmune diseases based on modulation of the immune response. Yet therapeutic modulation has...
6.
Kong Y, Morris G, Brown N, Yan Y, Flynn J, David C
J Autoimmun
. 2009 Oct;
33(3-4):239-46.
PMID: 19822405
Murine experimental autoimmune thyroiditis (EAT) is a model for Hashimoto's thyroiditis that has served as a prototype of T cell-mediated autoimmunity for more than three decades. Key roles for MHC...
7.
Jacob J, Kong Y, Nalbantoglu I, Snower D, Wei W
J Immunol
. 2009 Apr;
182(9):5873-81.
PMID: 19380836
Modulation of the immune system to amplify anti-tumor immunity carries the risk of developing autoimmune diseases, including hypothyroidism, as seen with cancer patients undergoing clinical trials for immunotherapeutic regimens. Although...
8.
Morris G, Brown N, Kong Y
J Autoimmun
. 2009 Apr;
33(1):68-76.
PMID: 19375891
Murine experimental autoimmune thyroiditis (EAT) is a model for Hashimoto's thyroiditis, an organ-specific autoimmune disease characterized by mononuclear cell infiltration and destruction of the thyroid gland. Susceptibility to EAT is...
9.
Dagdelen S, Kong Y, Banga J
Endocrinol Metab Clin North Am
. 2009 Mar;
38(2):343-54, viii.
PMID: 19328415
Graves' disease affects only humans. Although it is a treatable illness, medical therapy with antithyroid drugs is imperfect, showing high rates of recurrence. Furthermore, the etiology and treatment of the...
10.
Kong Y, Jacob J, Flynn J, Elliott B, Wei W
Autoimmun Rev
. 2009 Mar;
9(1):28-33.
PMID: 19254781
Improving cancer immunotherapy by targeting T cell network also triggers autoimmunity. We disrupted regulatory T cell (Treg) function to probe the balance between breast cancer vaccination and autoimmune thyroiditis (EAT)...