Yeva Mirzakhanyan
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Explore the profile of Yeva Mirzakhanyan including associated specialties, affiliations and a list of published articles.
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11
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99
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Recent Articles
1.
Mirzakhanyan Y, Jankevics A, Scheltema R, Gershon P
mBio
. 2023 Aug;
14(5):e0113523.
PMID: 37646531
An outstanding problem in the understanding of poxvirus biology is the molecular structure of the mature virion. Via deep learning methods combined with chemical cross-linking mass spectrometry, we have addressed...
2.
Ziegler M, Sorensen A, Banyard D, Sayadi L, Chnari E, Hatch M, et al.
Plast Reconstr Surg
. 2022 Oct;
151(1):108-117.
PMID: 36219861
Background: Autologous fat grafting is commonly used for soft-tissue repair (approximately 90,000 cases per year in the United States), but outcomes are limited by volume loss (20% to 80%) over...
3.
Weghorst F, Mirzakhanyan Y, Hernandez K, Gershon P, Cramer K
Front Cell Dev Biol
. 2022 Mar;
10:844844.
PMID: 35330912
The auditory brainstem relies on precise circuitry to facilitate sound source localization. In the chick, the development of this specialized circuitry requires non-apoptotic activity of caspase-3, for which we previously...
4.
Weghorst F, Mirzakhanyan Y, Samimi K, Dhillon M, Barzik M, Cunningham L, et al.
Front Cell Neurosci
. 2020 Dec;
14:573345.
PMID: 33281555
Sound localization requires extremely precise development of auditory brainstem circuits, the molecular mechanisms of which are largely unknown. We previously demonstrated a novel requirement for non-apoptotic activity of the protease...
5.
Pal S, Mirzakhanyan Y, Gershon P, Tifrea D, de la Maza L
NPJ Vaccines
. 2020 Oct;
5:87.
PMID: 33014435
The goal of this study was to determine if exosomes, isolated from infected HeLa cells (-exosomes), induce protective immune responses in mice following vaccination using CpG plus Montanide as adjuvants....
6.
Mirzakhanyan Y, Gershon P
J Virol
. 2020 Oct;
94(24).
PMID: 32999026
We conducted an exhaustive search for three-dimensional structural homologs to the proteins of 20 key phylogenetically distinct nucleocytoplasmic DNA viruses (NCLDV). Structural matches covered 429 known protein domain superfamilies, with...
7.
Liu R, Olano L, Mirzakhanyan Y, Gershon P, Moss B
Cell Rep
. 2019 Oct;
29(4):816-828.e6.
PMID: 31644906
IFITs are interferon-induced proteins that can bind 5'-triphosphate or ribose-unmethylated capped ends of mRNA to inhibit translation. Although some viruses avoid IFITs by synthesizing RNAs with eukaryotic-like caps, no viral...
8.
Sandoval R, Boyd R, Kiszter A, Mirzakhanyan Y, Santibanez P, Gershon P, et al.
Plant J
. 2019 May;
99(6):1116-1126.
PMID: 31077462
The mitochondrial and chloroplast mRNAs of the majority of land plants are modified through cytidine to uridine (C-to-U) RNA editing. Previously, forward and reverse genetic screens demonstrated a requirement for...
9.
Mirzakhanyan Y, Gershon P
PLoS Pathog
. 2019 Jan;
15(1):e1007508.
PMID: 30615658
We have investigated the molecular-level structure of the Vaccinia virion in situ by protein-protein chemical crosslinking, identifying 4609 unique-mass crosslink ions at an effective FDR of 0.33%, covering 2534 unique...
10.
Mirzakhanyan Y, Gershon P
Microbiol Mol Biol Rev
. 2017 Jul;
81(3).
PMID: 28701329
The past 17 years have been marked by a revolution in our understanding of cellular multisubunit DNA-dependent RNA polymerases (MSDDRPs) at the structural level. A parallel development over the past...