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Yechun Pei

Explore the profile of Yechun Pei including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 45
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Recent Articles
11.
Pei J, Xiao Z, Guo Z, Pei Y, Wei S, Wu H, et al.
Diabetes Metab Syndr Obes . 2020 Oct; 13:3887-3898. PMID: 33116735
Introduction: This study aimed to investigate the role of β adrenergic receptor (βAR) in insulin signaling transduction in H9C2 cardiomyoblast cells to understand the formation of the βAR-insulin receptor (IR)...
12.
Wu H, Wei S, Huang Y, Chen L, Wang Y, Wu X, et al.
FASEB J . 2020 Feb; 34(4):5092-5105. PMID: 32067279
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β-amyloid peptide 1-42 (Aβ ), and neuronal loss. The self-association of Aβ monomers (Aβ-M) into...
13.
Zhou Y, Chen L, Zhou X, Pei Y, Wei S, Mehmood A, et al.
J Appl Bioinforma Comput Biol . 2019 May; 7(3). PMID: 31058201
Alzheimer's disease (AD) is a lifelong progressive neurodegenerativa disease related with accumulation of amyloid β peptide (Aβ) produced by processing of amyloid precursor protein (APP) in the brain. In spite...
14.
Pei J, Wei S, Pei Y, Wu H, Wang D
Curr Med Chem . 2019 Apr; 27(21):3555-3576. PMID: 30963964
Gluten triggers Celiac Disease (CD) and type I diabetes in genetically predisposed population of human leukocyte antigen DQ2/DQ8+ and associates with disorders such as schizophrenia and autism. Application of a...
15.
Wei S, Pei Y, Wang Y, Guan H, Huang Y, Xing T, et al.
Biochimie . 2018 Dec; 158:73-81. PMID: 30576774
Keap1 is deemed as a suppressor of Nrf2 in cytoplasm by sequestrating Nrf2 to proteolysis as an adapter of the Cul3-Rbx1 E3 ubiquitin ligase complex. In the study, it was...
16.
Wang Y, Wei S, Chen L, Pei J, Wu H, Pei Y, et al.
PLoS One . 2017 Dec; 12(11):e0188261. PMID: 29190643
Troxerutin, a semi-synthetic derivative of the natural bioflavanoid rutin, has been reported to possess many beneficial effects in human bodies, such as vasoprotection, immune support, anti-inflammation and anti-aging. However, the...
17.
Geng S, Zhong Y, Zhou X, Zhao G, Xie X, Pei Y, et al.
Front Immunol . 2017 Jun; 8:663. PMID: 28638384
Regulatory T cells (Tregs) restrict overexuberant lymphocyte activation. While close proximity between Tregs and their suppression targets is important for optimal inhibition, and literature indicates that draining lymph nodes (LNs)...
18.
Huang Y, Pei Y, Guan H, Wei S, Wu H, Zhou Y, et al.
Pharm Res . 2017 Jan; 34(4):793-799. PMID: 28127707
Purpose: Adrenocorticotropic hormone (ACTH) is the only medicine for treating infantile spasms, however, it is catabolized rapidly. In order to make an ACTH derivative with prolonged effects, we prepared genetically...
19.
Pei Y, Geng S, Liu L, Yan F, Guan H, Hou J, et al.
Hum Vaccin Immunother . 2013 Jan; 9(5):1019-31. PMID: 23324570
Pet allergens are major causes for asthma and allergic rhinitis. Fel d 1 protein, a key pet allergen from domestic cat, can sensitize host and trigger asthma attack. In this...