Yea-Lih Lin
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Explore the profile of Yea-Lih Lin including associated specialties, affiliations and a list of published articles.
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52
Citations
2049
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Recent Articles
1.
Younas M, Gimenez S, Lin Y, Mettling C, Maiorano D, Reynes J, et al.
J Infect Dis
. 2025 Feb;
PMID: 39903648
Background: In order to better understand why about 15% of people living with Human Immunodeficiency Virus-1 (PWH) on highly active antiretroviral therapy do not restore their CD4 count, we explored...
2.
Coquel F, Ho S, Tsai K, Yang C, Aze A, Devin J, et al.
Elife
. 2025 Jan;
13.
PMID: 39887032
Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability. This feature is exploited by cancer therapies to either increase RS to...
3.
Lee M, Chung Y, Thenaka P, Wang Y, Lin Y, Kan N
Int J Med Sci
. 2024 Jul;
21(9):1689-1700.
PMID: 39006847
There is evidence that aging and obesity are associated with increased oxidative stress and chronic inflammation. High-intensity interval training (HIIT) may be superior to moderate-intensity continuous training (MICT) in anti-inflammatory...
4.
Techer H, Gopaul D, Heuze J, Bouzalmad N, Leray B, Vernet A, et al.
Nat Commun
. 2024 Jun;
15(1):5423.
PMID: 38926338
Oncogene-induced senescence (OIS) arrests cell proliferation in response to replication stress (RS) induced by oncogenes. OIS depends on the DNA damage response (DDR), but also on the cGAS-STING pathway, which...
5.
Heuze J, Kemiha S, Barthe A, Vilarrubias A, Aouadi E, Aiello U, et al.
EMBO J
. 2023 Oct;
42(23):e113104.
PMID: 37855233
R-loops represent a major source of replication stress, but the mechanism by which these structures impede fork progression remains unclear. To address this question, we monitored fork progression, arrest, and...
6.
Heuze J, Lin Y, Lengronne A, Poli J, Pasero P
C R Biol
. 2023 Oct;
346:95-105.
PMID: 37779381
Replication stress is an alteration in the progression of replication forks caused by a variety of events of endogenous or exogenous origin. In precancerous lesions, this stress is exacerbated by...
7.
Ovejero S, Viziteu E, Dutrieux L, Devin J, Lin Y, Alaterre E, et al.
Front Immunol
. 2022 Dec;
13:983181.
PMID: 36569948
Multiple myeloma (MM) is a hematologic cancer characterized by accumulation of malignant plasma cells in the bone marrow. To date, no definitive cure exists for MM and resistance to current...
8.
Kundura L, Gimenez S, Cezar R, Andre S, Younas M, Lin Y, et al.
J Allergy Clin Immunol
. 2022 Jul;
150(3):594-603.e2.
PMID: 35841981
Background: Lymphopenia is predictive of survival in patients with coronavirus disease 2019 (COVID-19). Objective: The aim of this study was to understand the cause of the lymphocyte count drop in...
9.
Devin J, Caneque T, Lin Y, Mondoulet L, Veyrune J, Abouladze M, et al.
Cancer Res
. 2022 Jan;
82(6):998-1012.
PMID: 35078814
Significance: Iron homeostasis represents a potential therapeutic target for high-risk patients with DLBCL that can be targeted with ironomycin to induce cell death and to sensitize tumor cells to conventional...
10.
Lin Y, Pasero P
Curr Opin Genet Dev
. 2021 Aug;
71:136-142.
PMID: 34455237
Replication stress (RS) is a hallmark of cancer cells that is associated with increased genomic instability. RS occurs when replication forks encounter obstacles along the DNA. Stalled forks are signaled...