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Yasutake Yano

Explore the profile of Yasutake Yano including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Nawata J, Yamamoto T, Tanaka S, Yano Y, Uchida T, Fujii S, et al.
Biochem Biophys Rep . 2023 Mar; 34:101449. PMID: 36926278
Left ventricular (LV) diastolic dysfunction is increasingly common in heart failure with preserved ejection fraction (HFpEF), and new drug therapy is desired. We recently reported that dantrolene (DAN) attenuates pressure-overload...
2.
Yano Y, Kobayashi S, Uchida T, Chang Y, Nawata J, Fujii S, et al.
Biochem Biophys Res Commun . 2022 Dec; 642:175-184. PMID: 36584481
Dantrolene (DAN) directly binds to cardiac ryanodine receptor 2 (RyR2) through Leu-Cys in the N-terminal domain and subsequently inhibits diastolic Ca leakage through RyR2. We previously reported that therapy using...
3.
Yoshitomi R, Kobayashi S, Yano Y, Nakashima Y, Fujii S, Nanno T, et al.
Heart . 2022 Jan; 108(6):429-437. PMID: 35078868
Objective: Sudden cardiac death (SCD) is the major cause of death in cardiac sarcoidosis (CS). We aimed to identify the prognostic markers for sustained ventricular tachycardia (sVT) and SCD in...