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Yasuo Tsutsumi

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Articles 223
Citations 2472
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Recent Articles
1.
Idehara W, Haga Y, Tsujino H, Ikuno Y, Manabe S, Hokaku M, et al.
Environ Res . 2025 Jan; 269:120934. PMID: 39862951
Microplastics (MPs), defined as plastic particles smaller than 5 mm, have garnered considerable attention owing to their potential biological impact on human health. These particles exhibit a range of physicochemical...
2.
Wada Y, Jang K, Ishii H, Watakabe Y, Tsutsumi M, Sako M, et al.
Chem Asian J . 2024 Nov; 20(2):e202401073. PMID: 39495489
We have successfully improved the fluorescence quantum yield of isoindolo[2,1-a]quinoline derivatives by suppressing the rotation of the phenyl groups at positions 5 and 11 (or 13). Additionally, we found that...
3.
Saeki Y, Higashisaka K, Izutani R, Seo J, Miyaji K, Haga Y, et al.
ACS Nanosci Au . 2024 Oct; 4(5):317-321. PMID: 39430372
Given that daily exposure to nanoparticles is now unavoidable, there are concerns that nanoparticles have unexpected biological effects due to their small size. Here, we examined the biodistribution of silver...
4.
Manabe S, Haga Y, Tsujino H, Ikuno Y, Asahara H, Higashisaka K, et al.
Sci Rep . 2024 Oct; 14(1):24008. PMID: 39402130
Background: Microplastics (MPs), plastic particles < 5 mm in size, are prevalent in the environment, and human exposure to them is inevitable. To assess the potential risk of MPs on...
5.
Simoni-Nieves A, Lindzen M, Giri S, Gupta N, Chatterjee R, Selvadurai B, et al.
Cell Rep Med . 2024 Aug; 5(9):101703. PMID: 39216477
Activating EGFR (epidermal growth factor receptor) mutations can be inhibited by specific tyrosine kinase inhibitors (TKIs), which have changed the landscape of lung cancer therapy. However, due to secondary mutations...
6.
Kobayashi J, Higashisaka K, Muranaka M, Xie Y, Okuno W, Haga Y, et al.
Biochem Biophys Res Commun . 2024 Aug; 736:150488. PMID: 39111054
Nanoparticles have useful functions due to the characteristics conferred on them by an increase in their specific surface area, and they have already been put into practical use in products...
7.
Ikuno Y, Tsujino H, Haga Y, Manabe S, Idehara W, Hokaku M, et al.
Ecotoxicol Environ Saf . 2024 Apr; 277:116346. PMID: 38669869
Microplastics, plastic particles 5 mm or less in size, are abundant in the environment; hence, the exposure of humans to microplastics is a great concern. Usually, the surface of microplastics...
8.
Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, et al.
Elife . 2024 Mar; 12. PMID: 38529532
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in...
9.
Konishi H, Haga Y, Okumura M, Tsujino H, Higashisaka K, Tsutsumi Y
Cell Death Discov . 2024 Mar; 10(1):108. PMID: 38429255
Various treatment options, such as molecular targeted drugs and immune checkpoint blockades, are available for patients with cancer. However, some cancer types are refractory to molecular targeted therapies or acquire...
10.
Moriwaki K, Yoshino A, Ikejiri Y, Nakamura R, Tsutsumi Y
Cureus . 2024 Feb; 16(1):e52589. PMID: 38371121
Complex regional pain syndrome (CRPS) type 1 is a chronic pain condition whose pathogenesis involves changes in the central and peripheral nervous systems, with potential genetic contributions. Functional magnetic resonance...