Yasunobu Mano
Overview
Explore the profile of Yasunobu Mano including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
279
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0
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Recent Articles
1.
Mano Y, Igarashi Y, Komori K, Hashimoto I, Watanabe H, Takahashi K, et al.
Front Immunol
. 2025 Feb;
16:1521278.
PMID: 39949777
The omentum is a common site of peritoneal metastasis in various cancers, including gastric cancer. It contains immune cell aggregates known as milky spots, which provide a microenvironment for peritoneal...
2.
Horaguchi S, Nakahara Y, Igarashi Y, Kouro T, Wei F, Murotani K, et al.
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200295
Neutrophil extracellular traps (NETs) released from neutrophils are related to cancer progression. However, the relationship between the therapeutic effects of immune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-PD-L1 antibodies...
3.
Nakahara Y, Kouro T, Motoyama S, Miura M, Fujita K, Igarashi Y, et al.
Front Cell Dev Biol
. 2024 Mar;
11:1324898.
PMID: 38469154
Clinical roles of plasma IL-6 levels have been reported in patients with various cancers, including non-small cell lung cancer (NSCLC), treated with immune checkpoint inhibitors (ICIs). However, the roles of...
4.
Wei F, Kouro T, Nakamura Y, Ueda H, Iiizumi S, Hasegawa K, et al.
Comput Struct Biotechnol J
. 2024 Feb;
23:859-869.
PMID: 38356658
Accurately identifying neoantigens is crucial for developing effective cancer vaccines and improving tumor immunotherapy. Mass spectrometry-based immunopeptidomics has emerged as a promising approach to identifying human leukocyte antigen (HLA) peptides...
5.
Kouro T, Higashijima N, Horaguchi S, Mano Y, Kasajima R, Xiang H, et al.
Int J Cancer
. 2024 Jan;
154(10):1828-1841.
PMID: 38212893
The selection of highly specific target antigens is critical for the development of clinically efficient and safe chimeric antigen receptors (CARs). In search of diagnostic marker for malignant mesothelioma (MM),...
6.
Himuro H, Nakahara Y, Igarashi Y, Kouro T, Higashijima N, Matsuo N, et al.
Cancer Immunol Immunother
. 2023 May;
72(8):2829-2840.
PMID: 37188764
Introduction: Immune checkpoint inhibitors (ICIs) have significantly improved the prognosis of non-small cell lung cancer (NSCLC). However, only a limited proportion of patients can benefit from this therapy, and clinically...
7.
Inoue T, Matsuda K, Matsusaka K, Nakajima M, Takeno Y, Miyazaki T, et al.
Chem Biol Interact
. 2022 Nov;
369:110257.
PMID: 36375514
Compounds with 3,4-fused tricyclic indole (FTI) frameworks are attractive scaffolds for drug discovery. We synthesized FTI-6D, a compound with this framework, which was cytotoxic in several human cancer cell lines....
8.
Hirasaki Y, Okabe A, Fukuyo M, Rahmutulla B, Mano Y, Seki M, et al.
Chem Biol Interact
. 2022 Apr;
360:109936.
PMID: 35447139
Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad, Bufo gargarizans. Bufanolides inhibit Na/K ATPase and have similar effects as cardiac glycosides, such as digitoxin or ouabain derived...
9.
Li W, Okabe A, Usui G, Fukuyo M, Matsusaka K, Rahmutulla B, et al.
Cancer Sci
. 2021 May;
112(8):3349-3362.
PMID: 34014591
Epstein-Barr virus (EBV) is associated with approximately 10% of gastric cancers (GCs). We previously showed that EBV infection of gastric epithelial cells induces aberrant DNA methylation in promoter regions, which...
10.
Sugiura M, Sato H, Okabe A, Fukuyo M, Mano Y, Shinohara K, et al.
Transl Oncol
. 2020 Oct;
14(1):100915.
PMID: 33096335
Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) under androgen deprivation therapy, by mechanisms e.g. expression of androgen receptor (AR) splice variant-7 (AR-V7). Here we conducted comprehensive epigenome and...