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Yasuko Nakajima

Explore the profile of Yasuko Nakajima including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 128
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Recent Articles
1.
Nakajima Y, Nakajima S
Methods Enzymol . 2010 Nov; 484:613-30. PMID: 21036253
Electrophysiological experiments in our laboratory have led to the discovery that the cholinergic neurons in the nucleus basalis in the rat forebrain possess constitutively active inward rectifier K(+) channels. Unlike...
2.
Yasufuku-Takano J, Nakajima S, Nakajima Y
J Neurosci Methods . 2007 Oct; 167(2):258-67. PMID: 17920133
We have developed dissociated primary cultures of the dorsal raphe nucleus from postnatal 9-12-day-old rats. The nucleus was dissected out from brain slices, dissociated, and cultured over a glial feeder...
3.
Kawano T, Zhao P, Floreani C, Nakajima Y, Kozasa T, Nakajima S
Mol Pharmacol . 2007 Feb; 71(4):1179-84. PMID: 17296805
Activation of substance P receptors, which are coupled to Galpha(q), inhibits the Kir3.1/3.2 channels, resulting in neuronal excitation. We have shown previously that this channel inactivation is not caused by...
4.
Zhao Q, Albsoul-Younes A, Zhao P, Kozasa T, Nakajima Y, Nakajima S
FEBS Lett . 2006 Jun; 580(16):3879-82. PMID: 16797547
HEK293 cells were transfected with cDNAs for Gbeta1(W332A) [a mutant Gbeta1], Ggamma2, and inward rectifier K+ channels (Kir3.1/Kir3.2). Application of Gbeta1gamma2 protein to these cells activated the K+ channels only...
5.
Koike-Tani M, Collins J, Kawano T, Zhao P, Zhao Q, Kozasa T, et al.
J Physiol . 2005 Feb; 564(Pt 2):489-500. PMID: 15731196
Certain transmitters inhibit Kir3 (GIRK) channels, resulting in neuronal excitation. We analysed signalling mechanisms for substance P (SP)-induced Kir3 inhibition in relation to the role of phosphatidylinositol 4,5-bisphosphate (PIP(2)). SP...
6.
Kawano T, Zhao P, Nakajima S, Nakajima Y
Neurosci Lett . 2004 Mar; 358(1):63-7. PMID: 15016435
G protein-coupled inward rectifier potassium channels (GIRK, Kir3) play a crucial role in determining neuronal excitability. Currently, four mammalian GIRK members (GIRK1-4) have been genetically identified. We have been investigating...
7.
Bajic D, Hoang Q, Nakajima S, Nakajima Y
J Neurosci Methods . 2004 Jan; 132(2):177-84. PMID: 14706715
The tuberomammillary nucleus (TMN) in the hypothalamus is the sole source of histamine in the brain. This nucleus, by innervating various brain regions, plays an important role for vital functions...
8.
Zhao Q, Kawano T, Nakata H, Nakajima Y, Nakajima S, Kozasa T
Mol Pharmacol . 2003 Oct; 64(5):1085-91. PMID: 14573757
G protein betagamma subunits bind and activate G protein-coupled inward rectifier K+ (GIRK) channels. This protein-protein interaction is crucial for slow hyperpolarizations of cardiac myocytes and neurons. The crystal structure...
9.
Stanfield P, Nakajima S, Nakajima Y
Rev Physiol Biochem Pharmacol . 2002 Sep; 145:47-179. PMID: 12224528
No abstract available.
10.
Chen L, Kawano T, Bajic S, Kaziro Y, Itoh H, Art J, et al.
Proc Natl Acad Sci U S A . 2002 May; 99(12):8430-5. PMID: 12034888
G protein-coupled inward rectifiers (GIRKs) are activated directly by G protein betagamma subunits, whereas classical inward rectifiers (IRKs) are constitutively active. We found that a glutamate residue of GIRK2 (E315),...