Yasser H Abdel-Wahab
Overview
Explore the profile of Yasser H Abdel-Wahab including associated specialties, affiliations and a list of published articles.
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10
Citations
43
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Recent Articles
1.
Graham G, Conlon J, Moffett R, Abdel-Wahab Y, Flatt P
J Pept Sci
. 2021 Apr;
27(8):e3328.
PMID: 33843129
The abilities of the long-acting, dual-agonist anti-diabetic peptides [D-Ala ]palmitoyl-lamprey GLP-1 and [D-Ser ]palmitoyl-paddlefish glucagon to induce α-cell to β-cell transdifferentiation were investigated in Glu ;ROSA26-eYFP mice. These animals have...
2.
Musale V, Moffett R, Conlon J, Flatt P, Abdel-Wahab Y
Peptides
. 2020 Dec;
136:170472.
PMID: 33338546
The antidiabetic actions of [A14K]PGLa-AM1, an analog of peptide glycine-leucine-amide-AM1 isolated from skin secretions of the octoploid frog Xenopus amieti, were investigated in genetically diabetic-obese db/db mice. Twice daily administration...
3.
Graham G, Conlon J, Abdel-Wahab Y, Flatt P
Eur J Pharmacol
. 2020 Apr;
878:173101.
PMID: 32320703
This study has examined the in vitro and in vivo anti-diabetic properties of the peptidase-resistant analogues [D-Ser]palmitoyl-paddlefish glucagon and [D-Ser]palmitoyl-lamprey glucagon. The peptides stimulated insulin release from BRIN-BD11 clonal β-cells...
4.
Graham G, McCloskey A, Abdel-Wahab Y, Conlon J, Flatt P
Mol Cell Endocrinol
. 2019 Sep;
499:110584.
PMID: 31539596
Peptidase-resistant analogues of GLP-1 peptides from sea lamprey and paddlefish ([D-Ala]palmitoyl-lamprey GLP-1 and [D-Ala]palmitoyl-paddlefish GLP-1) produced significant (P ≤ 0.05) and concentration-dependent increases in insulin release from BRIN-BD11 clonal β-cells...
5.
Graham G, Conlon J, Abdel-Wahab Y, Flatt P
Peptides
. 2018 Nov;
110:19-29.
PMID: 30391422
The insulinotropic and antihyperglycaemic properties of glucagons from the sea lamprey (Petromyzontiformes), paddlefish (Acipenseriformes) and trout (Teleostei) and oxyntomodulin from dogfish (Elasmobranchii) and ratfish (Holocephali) were compared with those of...
6.
Graham G, Conlon J, Abdel-Wahab Y, Flatt P
Mol Cell Endocrinol
. 2018 Oct;
480:54-64.
PMID: 30312651
Glucagon-like peptides-1 (GLP-1)from phylogenetically ancient fish (lamprey, dogfish, ratfish, paddlefish and bowfin) and from a teleost, the rainbow trout produced concentration-dependent stimulations of insulin release from clonal β-cells and isolated...
7.
Graham G, Conlon J, Abdel-Wahab Y, Gault V, Flatt P
Peptides
. 2017 Nov;
100:182-189.
PMID: 29157578
The insulinotropic properties of zebrafish GIP (zfGIP) were assessed in vitro using clonal pancreatic β-cell lines and isolated mouse islets and acute effects on glucose tolerance and insulin release in...
8.
Conlon J, Mechkarska M, Abdel-Wahab Y, Flatt P
Peptides
. 2017 Sep;
100:275-281.
PMID: 28887047
Several frog skin peptides, first identified as result of their antimicrobial or immunomodulatory activities, have subsequently been shown to stimulate insulin release both in vitro and in vivo and so...
9.
Hannan J, Marenah L, Ali L, Rokeya B, Flatt P, Abdel-Wahab Y
J Endocrinol
. 2007 Jan;
192(1):159-68.
PMID: 17210753
Asparagus racemosus root has previously been reported to reduce blood glucose in rats and rabbits. In the present study, the effects of the ethanol extract and five partition fractions of...
10.
Mathews J, Flatt P, Abdel-Wahab Y
Br J Nutr
. 2006 Mar;
95(3):576-81.
PMID: 16512944
Diabetes mellitus is a complex metabolic disease characterised by glucose overproduction and under-utilisation. As the incidence of diabetes expands rapidly across the globe there is an urgent need to expand...