Yaozu Xiang
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Explore the profile of Yaozu Xiang including associated specialties, affiliations and a list of published articles.
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41
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1106
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Recent Articles
1.
Wang X, Xu Y, Yu C, Deng R, Chen Y, Jiang K, et al.
Eur Heart J
. 2025 Feb;
PMID: 39969161
Backgrounds And Aims: Patients with periodontitis (PD) are prone to developing myocardial infarction (MI), yet the prognosis and mechanisms remain unclear. Given the presumed close association of neutrophils with both...
2.
Zhang B, Wu Y, Zhou C, Xie J, Zhang Y, Yang X, et al.
BMC Med
. 2024 Sep;
22(1):361.
PMID: 39227800
Background: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized with progressive cardiac fibrosis and heart failure. However, the exact mechanism driving the progression of cardiac fibrosis and heart failure in...
3.
Jiang K, Hwa J, Xiang Y
Pharmacol Res
. 2024 Jun;
205:107256.
PMID: 38866263
Inflammation is a crucial factor in cardiac remodeling after acute myocardial infarction (MI). Neutrophils, as the first wave of leukocytes to infiltrate the injured myocardium, exacerbate inflammation and cardiac injury....
4.
Zhang R, Xiang Y, Yang Y
J Am Chem Soc
. 2024 Jun;
146(25):17122-17130.
PMID: 38861703
DNA nanotechnology has emerged as a useful tool for constructing artificial channels penetrating the lipid bilayer. In this work, we introduce a stacked DNA origami nanochannel device characterized by a...
5.
Li X, You J, Dai F, Wang S, Yang F, Wang X, et al.
JACC Basic Transl Sci
. 2024 Jan;
8(12):1555-1573.
PMID: 38205342
A comprehensive view of the role of NLRP3/caspase-1/GSDMD-mediated pyroptosis in pressure overload cardiac hypertrophy is presented in this study. Furthermore, mitigation of NLRP3 deficiency-induced pyroptosis confers cardioprotection against pressure overload...
6.
Li S, Wang K, Jiang K, Xing D, Deng R, Xu Y, et al.
Biomaterials
. 2024 Jan;
305:122466.
PMID: 38184960
Inflammation is associated with a series of diseases like cancer, cardiovascular disease and infection, and phosphorylation/dephosphorylation modification of proteins are important in inflammation regulation. Here we designed and synthesized a...
7.
Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, et al.
Cell Rep
. 2023 Sep;
42(10):113174.
PMID: 37751357
The immune system plays a critical role during myocardial injury, contributing to repair and remodeling post myocardial infarction (MI). The myocardial infarct and border zone exhibit high heterogeneity, in turn...
8.
Zhang B, Wu Y, Yang X, Xiang Y, Yang B
Biomed Pharmacother
. 2023 Sep;
167:115448.
PMID: 37696084
Mutant desmoglein 2 (DSG2) is the second most common pathogenic gene in arrhythmogenic cardiomyopathy (ACM), accounting for approximately 10% of ACM cases. In addition to common clinical and pathological features,...
9.
Yarovinsky T, Su M, Chen C, Xiang Y, Tang W, Hwa J
Semin Immunol
. 2023 Jul;
69:101809.
PMID: 37478801
Pyroptosis is a form of programmed cell death associated with activation of inflammasomes and inflammatory caspases, proteolytic cleavage of gasdermin proteins (forming pores in the plasma membrane), and selective release...
10.
Rahman A, Li Y, Chan T, Zhao H, Xiang Y, Chang X, et al.
Zool Res
. 2023 May;
44(3):591-603.
PMID: 37147910
Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical translation. Nonetheless, current cardioprotective strategies/interventions formulated in preclinical cardiovascular research are...