Yannick Morias
Overview
Explore the profile of Yannick Morias including associated specialties, affiliations and a list of published articles.
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20
Citations
1157
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Recent Articles
1.
Voronova V, Sokolov V, Morias Y, Boezelman M, Wagberg M, Henricsson M, et al.
Front Pharmacol
. 2022 Dec;
13:993422.
PMID: 36518669
Abnormal branched-chained amino acids (BCAA) accumulation in cardiomyocytes is associated with cardiac remodeling in heart failure. Administration of branched-chain α-keto acid dehydrogenase (BCKD) kinase inhibitor BT2 has been shown to...
2.
Lahmar Q, Schouppe E, Morias Y, Van Overmeire E, De Baetselier P, Movahedi K, et al.
Cell Immunol
. 2021 Feb;
362:104296.
PMID: 33556903
Efficient priming of anti-tumor T cells requires the uptake and presentation of tumor antigens by immunogenic dendritic cells (DCs) and occurs mainly in lymph nodes draining the tumor (tdLNs). However,...
3.
Buler M, Naessens T, Mattsson J, Morias Y, Soderberg M, Robbins P, et al.
FASEB Bioadv
. 2020 Aug;
2(8):453-463.
PMID: 32821877
PGC1α-Related Coactivator (PRC) is a transcriptional coactivator promoting cytokine expression in vitro in response to mitochondrial injury and oxidative stress, however, its physiological role has remained elusive. Herein we investigate...
4.
Naessens T, Morias Y, Hamrud E, Gehrmann U, Budida R, Mattsson J, et al.
Am J Respir Crit Care Med
. 2020 Apr;
202(4):535-548.
PMID: 32255375
Emerging evidence supports a crucial role for tertiary lymphoid organs (TLOs) in chronic obstructive pulmonary disease (COPD) progression. However, mechanisms of immune cell activation leading to TLOs in COPD remain...
5.
Vanwalleghem G, Morias Y, Beschin A, Szymkowski D, Pays E
Sci Rep
. 2017 Jul;
7(1):6165.
PMID: 28733685
Infection of C57Bl/6 mice by pleomorphic African trypanosomes Trypanosoma brucei and T. congolense is characterized by parasitemia waves coupled with the production of systemic levels of TNF. This cytokine is...
6.
Igoe N, Bayle E, Tallant C, Fedorov O, Meier J, Savitsky P, et al.
J Med Chem
. 2017 Jul;
60(16):6998-7011.
PMID: 28714688
The bromodomain and plant homeodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of histone acetyltransferases of the MYST family to chromatin. Here, we describe NI-57 (16) as...
7.
Laoui D, Keirsse J, Morias Y, Van Overmeire E, Geeraerts X, Elkrim Y, et al.
Nat Commun
. 2016 Dec;
7:13720.
PMID: 28008905
Various steady state and inflamed tissues have been shown to contain a heterogeneous DC population consisting of developmentally distinct subsets, including cDC1s, cDC2s and monocyte-derived DCs, displaying differential functional specializations....
8.
Van Overmeire E, Stijlemans B, Heymann F, Keirsse J, Morias Y, Elkrim Y, et al.
Cancer Res
. 2015 Nov;
76(1):35-42.
PMID: 26573801
Tumors contain a heterogeneous myeloid fraction comprised of discrete MHC-II(hi) and MHC-II(lo) tumor-associated macrophage (TAM) subpopulations that originate from Ly6C(hi) monocytes. However, the mechanisms regulating the abundance and phenotype of...
9.
Morias Y, Abels C, Laoui D, Van Overmeire E, Guilliams M, Schouppe E, et al.
PLoS Pathog
. 2015 May;
11(5):e1004873.
PMID: 26020782
Monocytes consist of two well-defined subsets, the Ly6C+ and Ly6C- monocytes. Both CD11b+ myeloid cells populations have been proposed to infiltrate tissues during inflammation. While infiltration of Ly6C+ monocytes is...
10.
Zheng F, Devoogdt N, Sparkes A, Morias Y, Abels C, Stijlemans B, et al.
Immunobiology
. 2014 Dec;
220(2):200-9.
PMID: 25440182
Kupffer cells (KCs) are liver resident macrophages which are important for tissue homeostasis and have been implicated in immunogenic, tolerogenic and pathogenic immune reactions depending on the insult. These cells...