Yannic Nonnenmacher
Overview
Explore the profile of Yannic Nonnenmacher including associated specialties, affiliations and a list of published articles.
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15
Citations
773
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Recent Articles
1.
Henne A, Vigh A, Martens A, Nonnenmacher Y, Ohm M, Hosseini S, et al.
Front Mol Biosci
. 2023 Jan;
9:1084060.
PMID: 36619169
A reliable method for metabolite extraction is central to mass spectrometry-based metabolomics. However, existing methods are lengthy, mostly due to the step of scraping cells from cell culture vessels, which...
2.
Heinz A, Nonnenmacher Y, Henne A, Khalil M, Bejkollari K, Dostert C, et al.
Biochim Biophys Acta Mol Basis Dis
. 2022 Aug;
1868(12):166530.
PMID: 36038039
Macrophages undergo extensive metabolic reprogramming during classical pro-inflammatory polarization (M1-like). The accumulation of itaconate has been recognized as both a consequence and mediator of the inflammatory response. In this study...
3.
Kurniawan H, Franchina D, Guerra L, Bonetti L, -Baguet L, Grusdat M, et al.
Cell Metab
. 2020 Mar;
31(5):920-936.e7.
PMID: 32213345
Regulatory T cells (Tregs) maintain immune homeostasis and prevent autoimmunity. Serine stimulates glutathione (GSH) synthesis and feeds into the one-carbon metabolic network (1CMet) essential for effector T cell (Teff) responses....
4.
Nonnenmacher Y, Palorini R, Hiller K
Methods Mol Biol
. 2018 Oct;
1862:137-149.
PMID: 30315465
In this chapter, we present an experimental protocol for the targeted metabolic profiling of full cells and mitochondria in selectively permeabilized cells. Mitochondria of adherent cell cultures are made accessible...
5.
Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, et al.
Nature
. 2018 Aug;
560(7718):E28.
PMID: 30069041
In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample DD06....
6.
Hollinshead K, Munford H, Eales K, Bardella C, Li C, Escribano-Gonzalez C, et al.
Cell Rep
. 2018 Mar;
22(12):3107-3114.
PMID: 29562167
Since the discovery of mutations in isocitrate dehydrogenase 1 (IDH1) in gliomas and other tumors, significant efforts have been made to gain a deeper understanding of the consequences of this...
7.
Nonnenmacher Y, Hiller K
Cell Mol Life Sci
. 2018 Mar;
75(12):2093-2109.
PMID: 29502308
In the last decade, metabolism has been recognized as a major determinant of immunological processes. During an inflammatory response, macrophages undergo striking changes in their metabolism. This metabolic reprogramming is...
8.
Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, et al.
Nature
. 2017 Nov;
551(7680):384-388.
PMID: 29144447
The branched-chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer entities. However, the mechanistic role of BCAT1...
9.
Santos Silva L, Poschet G, Nonnenmacher Y, Becker H, Sapcariu S, Gaupel A, et al.
EMBO Rep
. 2017 Oct;
18(12):2172-2185.
PMID: 29066459
Elevated amino acid catabolism is common to many cancers. Here, we show that glioblastoma are excreting large amounts of branched-chain ketoacids (BCKAs), metabolites of branched-chain amino acid (BCAA) catabolism. We...
10.
Mak T, Grusdat M, Duncan G, Dostert C, Nonnenmacher Y, Cox M, et al.
Immunity
. 2017 Jun;
46(6):1089-1090.
PMID: 28636957
No abstract available.