Yankuan T Chen
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Explore the profile of Yankuan T Chen including associated specialties, affiliations and a list of published articles.
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6
Citations
23
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Recent Articles
1.
Zhao G, Zhang H, Chen Y, Shi K, Aghakeshmiri S, Yip F, et al.
Microorganisms
. 2024 Nov;
12(11).
PMID: 39597541
N6-methyladenosine (mA) is the most prevalent internal RNA modification. Here, we demonstrate that coxsackievirus B3 (CVB3), a common causative agent of viral myocarditis, induces mA modification primarily at the stop...
2.
Zhao G, Zhang H, Nasseri A, Yip F, Telkar N, Chen Y, et al.
Basic Res Cardiol
. 2024 Jun;
119(6):1075-1092.
PMID: 38834767
Nuclear factor of activated T cells 5 (NFAT5) is an osmosensitive transcription factor that is well-studied in renal but rarely explored in cardiac diseases. Although the association of Coxsackievirus B3...
3.
Lu D, Nagelberg A, Chow J, Chen Y, Michalchuk Q, Somwar R, et al.
Cancers (Basel)
. 2022 Mar;
14(6).
PMID: 35326531
Targeted therapies for exon 14-skipping ()-driven lung cancers have generated some promising results but response rates remain below that seen for other kinase-driven cancers. One strategy for improving treatment outcomes...
4.
Farnsworth D, Chen Y, de Rappard Yuswack G, Lockwood W
Cells
. 2021 Dec;
10(12).
PMID: 34944063
Epidermal growth factor receptor (EGFR) mutations are the molecular driver of a subset of non-small cell lung cancers (NSCLC); tumors that harbor these mutations are often dependent on sustained oncogene...
5.
Zhao G, Aghakeshmiri S, Chen Y, Zhang H, Yip F, Yang D
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34064510
The nuclear factor of activated T cells 5 (NFAT5) is well known for its sensitivity to cellular osmolarity changes, such as in the kidney medulla. Accumulated evidence indicates that NFAT5...
6.
Zhang H, Qiu Y, Zhao G, Wang H, Chen Y, Aghakeshmiri S, et al.
Cell Microbiol
. 2020 Feb;
22(7):e13198.
PMID: 32083795
Our previous study of coxsackievirus B3 (CVB3)-induced unfolded protein responses (UPR) found that overexpression of ATF6a enhances CVB3 VP1 capsid protein production and increases viral particle formation. These findings implicate...