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Yang-Fei Xing

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Chen S, Wu J, Liang Y, Tang Y, Song H, Wu L, et al.
Cancer Cell . 2020 Dec; 39(2):225-239.e8. PMID: 33357454
TP53 is the most frequently mutated gene in cancer, yet these mutations remain therapeutically non-actionable. Major challenges in drugging p53 mutations include heterogeneous mechanisms of inactivation and the absence of...