Yang-An Chuang
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Explore the profile of Yang-An Chuang including associated specialties, affiliations and a list of published articles.
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8
Citations
187
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Recent Articles
1.
Yang L, Liu W, Shi L, Wu J, Zhang W, Chuang Y, et al.
Biol Psychiatry
. 2023 Feb;
94(9):706-720.
PMID: 36796600
Background: Memory deficits are central to many neuropsychiatric diseases. During acquisition of new information, memories can become vulnerable to interference, yet mechanisms that underlie interference are unknown. Methods: We describe...
2.
Zhang W, Chuang Y, Na Y, Ye Z, Yang L, Lin R, et al.
Mol Cell
. 2019 Jun;
75(1):13-25.e5.
PMID: 31151856
Arc is a synaptic protein essential for memory consolidation. Recent studies indicate that Arc originates in evolution from a Ty3-Gypsy retrotransposon GAG domain. The N-lobe of Arc GAG domain acquired...
3.
Ping L, Chuang Y, Hsu S, Tsai H, Cheng M
Genes (Basel)
. 2016 Nov;
7(11).
PMID: 27879657
A higher-than-expected frequency of schizophrenia in patients with 22q11.2 deletion syndrome suggests that chromosome 22q11.2 harbors the responsive genes related to the pathophysiology of schizophrenia. The gene, which maps to...
4.
Chuang Y, Hu T, Chen C, Hsu S, Tsai H, Cheng M
Schizophr Res
. 2016 Jul;
176(2-3):106-113.
PMID: 27464451
Activity-regulated cytoskeleton-associated protein (ARC), which interacts with the N-methyl-d-aspartate receptor (NMDAR) complex, is a critical effector molecule downstream of multiple neuronal signaling pathways. Dysregulation of the ARC/NMDAR complex can disrupt...
5.
Wang H, Ardiles A, Yang S, Tran T, Posada-Duque R, Valdivia G, et al.
J Neurosci
. 2016 Feb;
36(5):1723-9.
PMID: 26843652
Significance Statement: Bidirectional changes of synaptic strength are crucial for the encoding of new memories. Currently, the only activity-dependent mechanism known to support such bidirectional changes are long-term potentiation (LTP)...
6.
Hu T, Chen C, Chuang Y, Hsu S, Cheng M
Psychiatry Res
. 2015 Jun;
228(3):958-60.
PMID: 26119399
Abnormal myelination is considered as part of the pathophysiology of schizophrenia. We resequenced the genomic DNA of the EGR2, which has a specific function in the myelination of peripheral nervous...
7.
Zhang W, Wu J, Ward M, Yang S, Chuang Y, Xiao M, et al.
Neuron
. 2015 Apr;
86(2):490-500.
PMID: 25864631
Arc is a cellular immediate-early gene (IEG) that functions at excitatory synapses and is required for learning and memory. We report crystal structures of Arc subdomains that form a bi-lobar...
8.
Cheng M, Chuang Y, Lu C, Chen Y, Luu S, Li J, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2012 Jun;
39(1):149-55.
PMID: 22691714
Objective: Early growth response genes (EGR1, 2, 3, and 4) encode a family of nuclear proteins that function as transcriptional regulators. They are involved in the regulation of synaptic plasticity,...