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Yana Mikhaleva

Explore the profile of Yana Mikhaleva including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 44
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Recent Articles
1.
Tolstenkov O, Mikhaleva Y, Glover J
Curr Biol . 2023 Aug; 33(18):3872-3883.e6. PMID: 37643617
To gain insight into the evolution of motor control systems at the origin of vertebrates, we have investigated higher-order motor circuitry in the protochordate Oikopleura dioica. We have identified a...
2.
Tolstenkov O, Mikhaleva Y, Glover J
Dev Biol . 2022 Sep; 492:37-46. PMID: 36162551
We recently described calcium signaling in the appendicularian tunicate Oikopleura dioica during pre-gastrulation stages, and showed that regularly occurring calcium waves progress throughout the embryo in a characteristic spatiotemporal pattern...
3.
Mikhaleva Y, Tolstenkov O, Glover J
Dev Biol . 2019 Mar; 450(1):9-22. PMID: 30905687
We characterized spontaneous Ca2+ signals in Oikopleura dioica embryos from pre-fertilization to gastrula stages following injection of GCaMP6 mRNA into unfertilized eggs. The unfertilized egg exhibited regular, transient elevations in...
4.
Mikhaleva Y, Skinnes R, Sumic S, Thompson E, Chourrout D
Dev Biol . 2018 Sep; 443(2):117-126. PMID: 30217597
The mechanisms driving innovations that distinguish large taxons are poorly known and essentially accessible via a candidate gene approach. A spectacular acquisition by tunicate larvaceans is the house, a complex...
5.
Lynagh T, Mikhaleva Y, Colding J, Glover J, Pless S
Proc Natl Acad Sci U S A . 2018 Aug; 115(33):8430-8435. PMID: 30061402
Acid-sensing ion channels (ASICs) are proton-gated ion channels broadly expressed in the vertebrate nervous system, converting decreased extracellular pH into excitatory sodium current. ASICs were previously thought to be a...
6.
Mikhaleva Y, Kreneisz O, Olsen L, Glover J, Chourrout D
J Exp Zool B Mol Dev Evol . 2015 Feb; 324(2):114-27. PMID: 25676192
Using RNA interference, we have selectively perturbed neurotransmitter-related features of the larval swimming behavior of Oikopleura dioica, a tunicate with a central nervous system comprising about 130 neurons. We injected...