Yan Sai
Overview
Explore the profile of Yan Sai including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
300
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Recent Articles
1.
Liu H, Cheng J, Ye F, Dong X, Ge W, Wang X, et al.
Toxicol Res (Camb)
. 2025 Feb;
14(1):tfaf019.
PMID: 39968516
Nitrogen mustard (NM) belongs to vesicant agents. Blisters are one of the important characteristics of NM skin damage. It is urgent to further elucidate the mechanism and develop effective countermeasures...
2.
Sai Y, Ge W, Zhong L, Zhang Q, Xiao J, Shan Y, et al.
Curr Res Toxicol
. 2025 Jan;
8():100212.
PMID: 39834518
Rotenone is a natural compound from plants. It is widely used in pesticides because of highly toxic to insects and fish. However, lots of research has reported that rotenone has...
3.
Cheng J, Liu H, Yu W, Dong X, Sai Y, Ye F, et al.
Heliyon
. 2024 Sep;
10(17):e37401.
PMID: 39290288
Nitrogen mustard (NM) is a chemotherapeutic agent capable of alkylating nucleophilic proteins and DNA, causing severe cell damage. However, no reports have been on the dynamic changes in proteomics induced...
4.
Ye F, Wang X, Liu H, Dong X, Cheng J, Chen M, et al.
Chem Biol Interact
. 2023 Jul;
382:110643.
PMID: 37481222
To investigate the role of the liver kinase (LK) B1 protein, an activator of AMP-activated protein kinase (AMPK), in AMPK signaling suppression when exposed to vesicant, a kind of chemical...
5.
Xiao J, Zhang Q, Shan Y, Ye F, Zhang X, Cheng J, et al.
Mol Neurobiol
. 2023 Jun;
60(10):5915-5930.
PMID: 37380822
MOTS-c is a 16-amino acid mitochondrial-derived peptide reported to be involved in regulating energy metabolism. However, few studies have reported the role of MOTS-c on neuron degeneration. In this study,...
6.
Ye F, Zeng Q, Dan G, Zhao Y, Yu W, Cheng J, et al.
Toxicol Mech Methods
. 2022 Sep;
33(4):271-278.
PMID: 36106344
Using sulfur mustard analog 2-chloroethyl ethyl sulfide (CEES), we established an model by poisoning cultured immortalized human bronchial epithelial cells. Nile Red staining revealed lipids accumulated 24 h after a...
7.
Zhang X, Zhang Q, Shan Y, Xiao J, Cheng J, Ye F, et al.
Gene
. 2022 Feb;
822:146349.
PMID: 35182677
TDCPP is a flame retardant which has nervous and reproductive toxicity. Although there is a close association between nervous and reproductive system, the exact toxic mechanism of TDCPP in these...
8.
Yu W, Dong X, Dan G, Ye F, Cheng J, Zhao Y, et al.
Toxicol Lett
. 2021 Nov;
354:14-23.
PMID: 34757179
Respiratory system injury is the main cause of mortality for nitrogen mustard (NM)-induced damage. Previous studies indicate that reactive oxygen species (ROS) participates in NM-mediated respiratory injuries, but the detailed...
9.
Ye F, Dan G, Zhao Y, Yu W, Cheng J, Chen M, et al.
Toxicol Res (Camb)
. 2021 Nov;
10(5):1034-1044.
PMID: 34733488
Sulfur mustard (a type of vesicant) can directly damage lung bronchial epithelium via aerosol inhalation, and prevalent cell death is an early event that obstructs the respiratory tract. JNK/c-Jun is...
10.
Dong X, He Y, Ye F, Zhao Y, Cheng J, Xiao J, et al.
Clin Transl Med
. 2021 Feb;
11(2):e312.
PMID: 33634989
Nitrogen mustard (NM) causes severe skin injury with an obvious inflammatory response, which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti-inflammatory properties and is considered...