Yalda A Kharaz
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Explore the profile of Yalda A Kharaz including associated specialties, affiliations and a list of published articles.
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11
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101
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Recent Articles
1.
Walters M, Skovgaard K, Heegaard P, Fang Y, Kharaz Y, Bundgaard L, et al.
Equine Vet J
. 2025 Jan;
PMID: 39775906
Background: MicroRNAs, a class of small noncoding RNAs, serve as post-transcriptional regulators of gene expression and are present in a stable and quantifiable form in biological fluids. MicroRNAs may influence...
2.
Kharaz Y, Zamboulis D, Fang Y, Welting T, Peffers M, Comerford E
Front Mol Biosci
. 2024 Jan;
10:1266088.
PMID: 38187089
The anterior cruciate ligament (ACL) is susceptible to degeneration, resulting in joint pain, reduced mobility, and osteoarthritis development. There is currently a paucity of knowledge on how anterior cruciate ligament...
3.
Anderson J, Johnson E, Jenkins R, Jacobsen S, Green D, Walters M, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834337
Extracellular vesicles (EVs) contribute to osteoarthritis pathogenesis through their release into joint tissues and synovial fluid. Synovial fluid-derived EVs have the potential to be direct biomarkers in the causal pathway...
4.
Readioff R, Geraghty B, Kharaz Y, Elsheikh A, Comerford E
Front Bioeng Biotechnol
. 2022 Dec;
10:984224.
PMID: 36457857
Proteoglycans (PGs) are minor extracellular matrix proteins, and their contributions to the mechanobiology of complex ligaments such as the cranial cruciate ligament (CCL) have not been determined to date. The...
5.
Kharaz Y, Goljanek-Whysall K, Nye G, Hurst J, McArdle A, Comerford E
Physiol Rep
. 2022 Aug;
10(16):e15426.
PMID: 35993414
Cruciate ligaments (CL) of the knee joint are injured following trauma or aging. MicroRNAs (miRs) are potential therapeutic targets in musculoskeletal disorders, but there is little known about the role...
6.
The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments
Kharaz Y, Birch H, Chester A, Alchorne E, Simpson D, Clegg P, et al.
Scand J Med Sci Sports
. 2021 Jul;
31(11):2033-2043.
PMID: 34271594
Injuries to the intra-articular anterior cruciate ligament (ACL) and the extra-articular medial collateral ligament (MCL) result in significant knee joint instability, pain, and immobility. Moderate endurance-type exercise can increase ligament...
7.
Balaskas P, Green J, Haqqi T, Dyer P, Kharaz Y, Fang Y, et al.
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32784773
Ageing is a leading risk factor predisposing cartilage to osteoarthritis. However, little research has been conducted on the effect of ageing on the expression of small non-coding RNAs (sncRNAs). RNA...
8.
Van Pelt D, Kharaz Y, Sarver D, Eckhardt L, Dzierzawski J, Disser N, et al.
Connect Tissue Res
. 2020 Jul;
62(1):24-39.
PMID: 32664808
Purpose/aim: Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease characterized by extensive muscle weakness. Patients with DMD lack a functional dystrophin protein, which transmits force and organizes the cytoskeleton...
9.
Gumucio J, Schonk M, Kharaz Y, Comerford E, Mendias C
JCI Insight
. 2020 May;
5(13).
PMID: 32463804
Scleraxis is a basic helix-loop-helix transcription factor that plays a central role in promoting tenocyte proliferation and matrix synthesis during embryonic tendon development. However, the role of scleraxis in the...
10.
Kharaz Y, Canty-Laird E, Tew S, Comerford E
J Anat
. 2018 Mar;
232(6):943-955.
PMID: 29498035
Tendons and ligaments play key roles in the musculoskeletal system in both man and animals. Both tissues can undergo traumatic injury, age-related degeneration and chronic disease, causing discomfort, pain and...