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Yajing An

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Recent Articles
1.
An Y, Ni R, Zhuang L, Yang L, Ye Z, Li L, et al.
Mol Biomed . 2025 Jan; 6(1):4. PMID: 39841361
Tuberculosis (TB) remains a prominent global health challenge, with the World Health Organization documenting over 1 million annual fatalities. Despite the deployment of the Bacille Calmette-Guérin (BCG) vaccine and available...
2.
Zhuang L, Ali A, Yang L, Ye Z, Li L, Ni R, et al.
Infect Med (Beijing) . 2024 Dec; 3(4):100148. PMID: 39687693
Background: Tuberculosis (TB) remains a global public health challenge. The existing Bacillus Calmette-Guérin vaccine has limited efficacy in preventing adult pulmonary TB, necessitating the development of new vaccines with improved...
3.
Ma H, Zhang E, An Y, Wei Y, Zhang L
Mitochondrial DNA B Resour . 2024 Jun; 9(6):812-817. PMID: 38911521
In this study, we assembled high-quality chloroplast genomes of through a reference-guided approach using high-throughput Illumina sequencing reads. The resulting chloroplast genome assembly displayed a typical quadripartite structural organization, comprising...
4.
Zhang L, Zhang C, An Y, Zhu Q, Wang M
Genes (Basel) . 2023 Nov; 14(11). PMID: 38002978
This study introduces a meticulously constructed genome assembly at the chromosome level for the Rosaceae family species , a traditional Chinese medicinal herb. The final assembly encompasses 1272.71 megabases (Mb)...
5.
Guo X, An Y, Lu F, Liu F, Wang B
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298661
Lytic polysaccharide monooxygenases (LPMOs) can oxidatively break the glycosidic bonds of crystalline cellulose, providing more actionable sites for cellulase to facilitate the conversion of cellulose to cello-oligosaccharides, cellobiose and glucose....
6.
Guo X, Jiang L, An Y, Lu F, Liu F, Wang B
Enzyme Microb Technol . 2023 May; 168:110255. PMID: 37178549
Lytic polysaccharide monooxygenases (LPMOs) can oxidatively cleave the glycosidic bonds of crystalline polysaccharides, providing more accessible sites for polysaccharide hydrolases and promoting efficient conversion of biomass. In order to promote...
7.
Guo X, An Y, Liu F, Lu F, Wang B
Bioresour Technol . 2022 Aug; 362:127803. PMID: 35995343
Lytic polysaccharide monooxygenases (LPMOs) can catalyze polysaccharides by oxidative cleavage of glycosidic bonds and have catalytic activity for cellulose, hemicellulose, chitin, starch and pectin, thus playing an important role in...
8.
Guo X, An Y, Jiang L, Zhang J, Lu F, Liu F
Int J Biol Macromol . 2022 Jan; 203:457-465. PMID: 35065137
Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes, which can catalyze the oxidative cleavage of polysaccharide β-1,4 glycosidic bonds to improve the hydrolysis efficiency of the substrate by other glycoside hydrolases....
9.
Guo X, Chai C, An Y, Peng C, Shi N, Wang W, et al.
Int J Biol Macromol . 2021 Feb; 175:262-269. PMID: 33561461
A high-throughput screening system was established by employing enhanced green fluorescent protein as a screenable fusion tag to evaluate the expression and secretion of a lytic polysaccharide monooxygenase (MtC1LPMO) using...
10.
Guo X, An Y, Chai C, Sang J, Jiang L, Lu F, et al.
Bioresour Technol . 2020 Aug; 317:124024. PMID: 32836036
To enhance the biomass conversion efficiency, the R17L mutant of the lytic polysaccharide monooxygenase (LPMO) MtC1LPMO with improved catalytic efficiency was constructed via rational point mutation based on the HotSpot...