Yajian Jiang
Overview
Explore the profile of Yajian Jiang including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
166
Followers
0
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Recent Articles
1.
Eagle K, Jiang Y, Shi X, Li M, Obholzer N, Hu T, et al.
Cell Stem Cell
. 2022 Apr;
29(4):650.
PMID: 35395189
No abstract available.
2.
Eagle K, Jiang Y, Shi X, Li M, Obholzer N, Hu T, et al.
Cell Stem Cell
. 2022 Feb;
29(3):386-399.e7.
PMID: 35108519
Deregulation of transcription is a hallmark of acute myeloid leukemia (AML) that drives oncogenic expression programs and presents opportunities for therapeutic targeting. By integrating comprehensive pan-cancer enhancer landscapes with genetic...
3.
Shi X, Jiang Y, Kitano A, Hu T, Murdaugh R, Li Y, et al.
Sci Adv
. 2021 Jul;
7(30).
PMID: 34290089
Metabolic dysregulation underlies malignant phenotypes attributed to cancer stem cells, such as unlimited proliferation and differentiation blockade. Here, we demonstrate that NAD metabolism enables acute myeloid leukemia (AML) to evade...
4.
Jiang Y, Hu T, Wang T, Shi X, Kitano A, Eagle K, et al.
Blood
. 2019 Nov;
134(24):2183-2194.
PMID: 31697807
Altered metabolism fuels 2 hallmark properties of cancer cells: unlimited proliferation and differentiation blockade. Adenosine monophosphate-activated protein kinase (AMPK) is a master regulator of bioenergetics crucial for glucose metabolism in...
5.
Hu T, Morita K, Hill M, Jiang Y, Kitano A, Saito Y, et al.
Blood
. 2019 Jul;
134(7):614-625.
PMID: 31270104
Oncogenic mutations confer on cells the ability to propagate indefinitely, but whether oncogenes alter the cell fate of these cells is unknown. Here, we show that the transcriptional regulator PRDM16s...
6.
Shi X, Kitano A, Jiang Y, Luu V, Hoegenauer K, Nakada D
Exp Hematol
. 2018 May;
64:33-44.e5.
PMID: 29751067
Recent advances in next-generation sequencing have identified novel mutations and revealed complex genetic architectures in human hematological malignancies. Moving forward, new methods to quickly generate animal models that recapitulate the...
7.
Jiang Y, Nakada D
Int J Hematol
. 2016 Feb;
103(6):607-16.
PMID: 26897135
Metabolic homeostasis is a fundamental property of cells that becomes dysregulated in cancer to meet the altered, often heightened, demand for metabolism for increased growth and proliferation. Oncogenic mutations can...
8.
Ke Q, He F, Lu L, Yu P, Jiang Y, Weng C, et al.
Neuromuscul Disord
. 2015 Oct;
25(12):955-8.
PMID: 26433613
Primary hypokalemic periodic paralysis is an autosomal dominant skeletal muscle channelopathy. In the present study, we investigated the genotype and phenotype of a Chinese hypokalemic periodic paralysis family. We used...
9.
Jiang Y, Liu M, Li Z, Jiang Y
Hepatogastroenterology
. 2014 Apr;
60(128):1825-32.
PMID: 24719914
Background/aims: Pancreatic cancer is one of the most aggressive tumors in mankind. Its aggressiveness is only due to the biological progressive characteristics but also the difficulty for clinical early detection...
10.
Jiang Y, Hu K, Xie W, Zheng G, Sun J, Zheng Y, et al.
Oncol Lett
. 2014 Jan;
7(2):419-422.
PMID: 24396459
Neutropenia is a common side-effect in hyperthyroid patients with long-term use of antithyroid drugs. This may be caused by drug-induced immune dysfunction or increased thyroxine hematologic toxicity, which usually returns...