Yael Friedmann
Overview
Explore the profile of Yael Friedmann including associated specialties, affiliations and a list of published articles.
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11
Citations
415
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Recent Articles
1.
Sharon A, Shmoel N, Erez H, Jankowski M, Friedmann Y, Spira M
Front Neurosci
. 2021 Dec;
15:764448.
PMID: 34880722
Despite increasing use of multielectrode array (MEA) implants for basic research and medical applications, the critical structural interfaces formed between the implants and the brain parenchyma, remain elusive. Prevailing view...
2.
Ambastha V, Friedmann Y, Leshem Y
Sci Rep
. 2020 Feb;
10(1):3291.
PMID: 32094490
Plant responses to salinity have been extensively studied over the last decades. Despite the vast accumulated knowledge, the ways Arabidopsis lateral roots (LR) cope with lethal salinity has not been...
3.
Dror S, Sander L, Schwartz H, Sheinboim D, Barzilai A, Dishon Y, et al.
Nat Cell Biol
. 2016 Aug;
18(9):1006-17.
PMID: 27548915
Melanoma originates in the epidermis and becomes metastatic after invasion into the dermis. Prior interactions between melanoma cells and dermis are poorly studied. Here, we show that melanoma cells directly...
4.
Lalzar I, Friedmann Y, Gottlieb Y
Environ Microbiol
. 2014 Mar;
16(12):3657-68.
PMID: 24650112
Arthropod symbionts present tissue tropism that corresponds to the nature of the association and the mode of transmission between host generations. In ticks, however, our knowledge of symbiont tissue tropism...
5.
Steiner L, Blum G, Friedmann Y, Levitzki A
Eur J Pharmacol
. 2007 Mar;
562(1-2):1-11.
PMID: 17376430
The insulin-like growth factor-1 receptor (IGF-1 receptor) is a receptor tyrosine kinase, highly homologous to the insulin receptor. In contrast to the insulin receptor, which is mostly involved in metabolic...
6.
Friedmann Y, Shriki A, Bennett E, Golos S, Diskin R, Marbach I, et al.
Mol Pharmacol
. 2006 Jul;
70(4):1395-405.
PMID: 16847144
In vivo screening of compounds for potential pharmacological activity is more advantageous than in vitro screening. In vivo screens eliminate the isolation of compounds that cannot cross biological membranes, are...
7.
Zcharia E, Metzger S, Chajek-Shaul T, Aingorn H, Elkin M, Friedmann Y, et al.
FASEB J
. 2004 Feb;
18(2):252-63.
PMID: 14769819
We have generated homozygous transgenic mice (hpa-tg) overexpressing human heparanase (endo-beta-D-glucuronidase) in all tissues and characterized the involvement of the enzyme in tissue morphogenesis, vascularization, and energy metabolism. Biochemical analysis...
8.
Goldshmidt O, Zcharia E, Abramovitch R, Metzger S, Aingorn H, Friedmann Y, et al.
Proc Natl Acad Sci U S A
. 2002 Jul;
99(15):10031-6.
PMID: 12097647
The present study emphasizes the importance of cell surface expression and secretion of heparanase (endo-beta-D-glucuronidase) in tumor angiogenesis and metastasis. For this purpose, nonmetastatic Eb mouse lymphoma cells were transfected...
9.
Haimov-Kochman R, Friedmann Y, Prus D, Goldman-Wohl D, Greenfield C, Anteby E, et al.
Mol Hum Reprod
. 2002 May;
8(6):566-73.
PMID: 12029075
Degradation of extracellular matrix (ECM) components is critical for invasion. Heparan sulphate proteoglycans are abundant in the ECM of the placenta and the decidua, hence their degradation may disassemble the...
10.
Vlodavsky I, Goldshmidt O, Zcharia E, Atzmon R, Elkin M, Peretz T, et al.
Semin Cancer Biol
. 2002 May;
12(2):121-9.
PMID: 12027584
Cleavage of heparan sulphate proteoglycans (HSPGs) affects the integrity and functional state of tissues and thereby fundamental normal and pathological phenomena involving cell migration and response to changes in the...