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Ya-Ning Shi

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Articles 18
Citations 251
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Recent Articles
1.
Zhang S, Zhu N, Shi Y, Zeng Q, Zhang C, Li H, et al.
Phytomedicine . 2024 May; 129:155614. PMID: 38692078
Background: Cellular senescence is an emerging hallmark of cancers, primarily fuels cancer progression by expressing senescence-associated secretory phenotype (SASP). Caveolin-1 (CAV1) is a key mediator of cell senescence. Previous studies...
2.
Li H, Zhu N, Wu J, Shi Y, Gu J, Qin L
Curr Pharm Des . 2024 Apr; 30(16):1265-1278. PMID: 38584553
Background: Targeting immunogenic cell death (ICD) is considered a promising therapeutic strategy for cancer. However, the commonly identified ICD inducers promote the expression of programmed cell death ligand 1 (PD-L1)...
3.
Zhang S, Shi Y, Gu J, He P, Ai Q, Zhou X, et al.
Pharm Biol . 2023 Jul; 61(1):1108-1119. PMID: 37462387
Context: Dihydromyricetin (DMY) is extracted from vine tea, a traditional Chinese herbal medicine with anti-cancer, liver protection, and cholesterol-lowering effects. Objective: This study investigated the mechanism of DMY against hepatocellular...
4.
Gu J, Shi Y, Zhu N, Li H, Zhang C, Qin L
Biomed Pharmacother . 2023 Jun; 164:114981. PMID: 37285754
Lipid metabolism disorders are pivotal in the development of various lipid-related diseases, such as obesity, atherosclerosis, non-alcoholic fatty liver disease, type 2 diabetes, and cancer. Celastrol, a bioactive compound extracted...
5.
Qiu Y, Shi Y, Zhu N, Zhang S, Zhang C, Gu J, et al.
Int J Biol Sci . 2023 May; 19(8):2333-2348. PMID: 37215994
Pyroptosis is a novel pro-inflammatory cell programmed death dependent on Gasdermin (GSMD) family-mediated membrane pore formation and subsequent cell lysis, accompanied by the release of inflammatory factors and expanding inflammation...
6.
Lin X, Shi Y, Cao Y, Tan X, Zeng Y, Luo S, et al.
Front Pharmacol . 2022 Oct; 13:960140. PMID: 36304153
In recent years, small intestine as a key target in the treatment of Inflammatory bowel disease caused by NSAIDs has become a hot topic. Sanguinarine (SA) is one of the...
7.
Shi Y, Liu L, Deng C, Zhao T, Shi Z, Yan J, et al.
Int J Biol Sci . 2021 Jul; 17(10):2561-2575. PMID: 34326694
Neointimal hyperplasia caused by the excessive proliferation of vascular smooth muscle cells (VSMCs) is the pathological basis of restenosis. However, there are few effective strategies to prevent restenosis. Celastrol, a...
8.
Zhao T, Zhu N, Shi Y, Wang Y, Zhang C, Deng C, et al.
J Cell Physiol . 2021 May; 236(11):7853-7873. PMID: 34018609
Epidemiological studies have shown that plasma HDL-C levels are closely related to the risk of prostate cancer, breast cancer, and other malignancies. As one of the key carriers of cholesterol...
9.
Zhang Y, Shi Y, Zhu N, Zhao T, Guo Y, Liao D, et al.
J Drug Target . 2020 Dec; 29(5):467-475. PMID: 33269623
Vascular remodelling refers to abnormal changes in the structure and function of blood vessel walls caused by injury, and is the main pathological basis of cardiovascular diseases such as atherosclerosis,...
10.
Wang W, Zhu N, Yan T, Shi Y, Chen J, Zhang C, et al.
Cell Commun Signal . 2020 Aug; 18(1):119. PMID: 32746850
Exosomes have been considered as novel and potent vehicles of intercellular communication, instead of "cell dust". Exosomes are consistent with anucleate cells, and organelles with lipid bilayer consisting of the...