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Ya-Fang Shih

Explore the profile of Ya-Fang Shih including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 31
Followers 0
Related Specialties
Biochemistry
Cell Biology
Molecular Biology
Top 10 Co-Authors
Chien-Chung Yang
Li-Der Hsiao
Chuen-Mao Yang
Hui-Ching Tseng
Chih-Kai Hsu
Ching-I Chang
Wun-Hsin Hsu
Hsin-Hui Lin
Zih-Yao Yu
Wei-Ning Lin
Published In
Int J Mol Sci
Oxid Med Cell Longev
Antioxidants (Basel)
Mediators Inflamm
Affiliations
Soon will be listed here.
Recent Articles
1.
Tumor Necrosis Factor-α-Induced C-C Motif Chemokine Ligand 20 Expression through TNF Receptor 1-Dependent Activation of EGFR/p38 MAPK and JNK1/2/FoxO1 or the NF-κB Pathway in Human Cardiac Fibroblasts
Yang C, Yang C, Hsu W, Hsiao L, Tseng H, Shih Y
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012347
Tumor necrosis factor (TNF)-α is involved in the pathogenesis of cardiac injury, inflammation, and apoptosis. It is a crucial pro-inflammatory cytokine in many heart disorders, including chronic heart failure and...
2.
Thrombin Induces COX-2 and PGE Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells
Yang C, Hsiao L, Shih Y, Hsu C, Hu C, Yang C
Mediators Inflamm . 2022 May; 2022:4600029. PMID: 35497094
The inflammation of the airway and lung could be triggered by upregulation cyclooxygenase (COX)-2 and prostaglandin E (PGE) induced by various proinflammatory factors. COX-2 induction by thrombin has been shown...
3.
HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells
Yang C, Hsiao L, Wang C, Lin W, Shih Y, Chen Y, et al.
Antioxidants (Basel) . 2022 Apr; 11(4). PMID: 35453467
Lung inflammation is a pivotal event in the pathogenesis of acute lung injury. Heme oxygenase-1 (HO-1) is a key antioxidant enzyme that could be induced by kaempferol (KPR) and exerts...
4.
Induction of Heme Oxygenase-1 by 15d-Prostaglandin J Mediated via a ROS-Dependent Sp1 and AP-1 Cascade Suppresses Lipopolysaccharide-Triggered Interleukin-6 Expression in Mouse Brain Microvascular Endothelial Cells
Yang C, Hsiao L, Shih Y, Chang C, Yang C
Antioxidants (Basel) . 2022 Apr; 11(4). PMID: 35453404
Heme oxygenase-1 (HO-1) has been shown to exert antioxidant, anti-inflammatory, and anti-apoptotic effects in various types of cells. Therefore, the induction of HO-1 is an excellent rationale for the development...
5.
5,8-Dihydroxy-4 ', 7-dimethoxyflavone Attenuates TNF--Induced Expression of Vascular Cell Adhesion Molecule-1 through EGFR/PKC/PI3K/Akt/Sp1-Dependent Induction of Heme Oxygenase-1 in Human Cardiac Fibroblasts
Yang C, Hsiao L, Shih Y, Lin H, Yang C
Oxid Med Cell Longev . 2022 Mar; 2022:1372958. PMID: 35281466
Recently, we found that 5,8-dihydroxy-4',7-dimethoxyflavone (DDF) upregulated the expression of heme oxygenase (HO)-1 via p38 mitogen-activated protein kinase/nuclear factor-erythroid factor 2-related factor 2 (MAPK/Nrf2) pathway in human cardiac fibroblasts (HCFs)....
6.
Sphingosine 1-Phosphate-Upregulated COX-2/PGE System Contributes to Human Cardiac Fibroblast Apoptosis: Involvement of MMP-9-Dependent Transactivation of EGFR Cascade
Yang C, Hsiao L, Shih Y, Su M, Yang C
Oxid Med Cell Longev . 2022 Mar; 2022:7664290. PMID: 35242277
Human cardiac fibroblasts (HCFs) play key roles in normal physiological functions and pathological processes in the heart. Our recent study has found that, in HCFs, sphingosine 1-phosphate (S1P) can upregulate...
7.
Anti-Inflammatory Effects of Rhamnetin on Bradykinin-Induced Matrix Metalloproteinase-9 Expression and Cell Migration in Rat Brain Astrocytes
Yang C, Hsiao L, Shih Y, Yu Z, Yang C
Int J Mol Sci . 2022 Jan; 23(2). PMID: 35054789
Bradykinin (BK) has been shown to induce matrix metalloproteinase (MMP)-9 expression and participate in neuroinflammation. The BK/MMP-9 axis can be a target for managing neuroinflammation. Our previous reports have indicated...