Y W Loke
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Explore the profile of Y W Loke including associated specialties, affiliations and a list of published articles.
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Articles
131
Citations
1799
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Recent Articles
1.
Moffett A, Loke Y
Placenta
. 2004 Mar;
25(1):1-8.
PMID: 15013633
The survival of the allogeneic conceptus has long been an immunological paradox. Medawar was the first to propose an evasive mechanism based on the concept of self/non-self recognition described in...
2.
Emmer P, Steegers E, van Lierop M, Loke Y, van der Meer A, Joosten I
Eur J Immunogenet
. 2003 Mar;
30(2):163-4.
PMID: 12648287
No abstract available.
3.
van Lierop M, Wijnands F, Loke Y, Emmer P, Lukassen H, Braat D, et al.
Mol Hum Reprod
. 2002 Aug;
8(8):776-84.
PMID: 12149411
Human leukocyte antigen (HLA)-G, which is mainly expressed at the maternal-fetal interface, may play a role in the immune tolerance of the semi-allogenic fetus by the mother. Functional studies have...
4.
Hiby S, Lough M, Keverne E, Surani M, Loke Y, King A
Hum Mol Genet
. 2001 May;
10(10):1093-100.
PMID: 11331620
Genomic imprinting is the phenomenon whereby mono-allelic expression of certain genes occurs depending on their parental origin. The observation that imprinting only occurs in placental mammals has led to the...
5.
van Wijk I, Griffioen S, Tjoa M, Mulders M, van Vugt J, Loke Y, et al.
Am J Obstet Gynecol
. 2001 Apr;
184(5):991-7.
PMID: 11303210
Objective: The aim of this study was to assess the use of circulating trophoblast cells in maternal peripheral blood for noninvasive prenatal diagnosis of numeric chromosomal aberrations. Study Design: A...
6.
Li X, Charnock-Jones D, Zhang E, Hiby S, Malik S, Day K, et al.
J Clin Endocrinol Metab
. 2001 Apr;
86(4):1823-34.
PMID: 11297624
Angiogenesis is essential for endometrial growth and repair, and disruption of this process may lead to common disorders of women, including menorrhagia and endometriosis. In pregnancy, failure of the endometrial...
7.
Davies B, Hiby S, Gardner L, Loke Y, King A
Am J Reprod Immunol
. 2001 Feb;
45(2):103-7.
PMID: 11216872
Problem: It has been proposed that the expression of the non-classical MHC class I antigen, HLA-G, by trophoblast is one mechanism by which the placenta evades attack by maternal uterine...
8.
Loke Y, King A
Baillieres Best Pract Res Clin Obstet Gynaecol
. 2000 Oct;
14(5):827-37.
PMID: 11023803
During implantation, the uterine decidua is invaded by extravillous trophoblast (EVT) cells whose function is to destroy the walls of the uterine spiral arteries in order to provide an adequate...
9.
Frumento G, Franchello S, Palmisano G, Nicotra M, Giacomini P, Loke Y, et al.
Tissue Antigens
. 2000 Aug;
56(1):30-7.
PMID: 10958353
HLA-G is an effective ligand of natural killer (NK) inhibitory receptors, HLA-G transcripts have been detected in several human tumors, and cytokines like gamma interferon (IFN) enable HLA-G molecules to...
10.
King A, Allan D, Bowen M, Powis S, Joseph S, Verma S, et al.
Eur J Immunol
. 2000 Jul;
30(6):1623-31.
PMID: 10898498
Non-classical MHC class I molecule HLA-E is the ligand for CD94/NKG2 NK cell receptors. Surface expression of HLA-E requires binding of specific HLA class I leader sequences. The uterine mucosa...