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Y Loriot

Explore the profile of Y Loriot including associated specialties, affiliations and a list of published articles. Areas
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Articles 68
Citations 1382
Followers 0
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Recent Articles
1.
Powles T, Tagawa S, Vulsteke C, Gross-Goupil M, Park S, Necchi A, et al.
Ann Oncol . 2025 Feb; PMID: 39934055
Background: Sacituzumab govitecan (SG), a Trop-2-directed antibody-drug conjugate, demonstrated efficacy and manageable toxicity in the phase II TROPHY-U-01 study in pretreated advanced urothelial carcinoma (aUC). We report the results from...
2.
Rosenberg J, Galsky M, Powles T, Petrylak D, Bellmunt J, Loriot Y, et al.
ESMO Open . 2024 Dec; 9(12):103972. PMID: 39642637
Background: The IMvigor210 trial demonstrated clinical benefit and manageable toxicity with atezolizumab monotherapy [anti-programmed death-ligand 1 (PD-L1)] in patients with metastatic urothelial carcinoma (UC) in primary analyses. Final efficacy and...
3.
Powles T, Bellmunt J, Comperat E, De Santis M, Huddart R, Loriot Y, et al.
Ann Oncol . 2024 Mar; 35(6):485-490. PMID: 38490358
No abstract available.
4.
Loriot Y, Petrylak D, Rezazadeh Kalebasty A, Flechon A, Jain R, Gupta S, et al.
Ann Oncol . 2024 Jan; 35(4):392-401. PMID: 38244927
Background: Sacituzumab govitecan (SG) is a Trop-2-directed antibody-drug conjugate containing cytotoxic SN-38, the active metabolite of irinotecan. SG received accelerated US Food and Drug Administration approval for locally advanced (LA)...
5.
Necchi A, Pouessel D, Leibowitz R, Gupta S, Flechon A, Garcia-Donas J, et al.
Ann Oncol . 2023 Nov; 35(2):200-210. PMID: 37956738
Background: Fibroblast growth factor receptor 3 (FGFR3) alterations are oncogenic drivers of urothelial carcinoma (UC). Pemigatinib is a selective, oral inhibitor of FGFR1-3 with antitumor activity. We report the efficacy...
6.
Blay J, Cropet C, Mansard S, Loriot Y, de la Fouchardiere C, Haroche J, et al.
ESMO Open . 2023 Nov; 8(6):102038. PMID: 37922690
Background: BRAF inhibitors are approved in BRAF-mutated metastatic melanoma, non-small-cell lung cancer (NSCLC), Erdheim-Chester disease (ECD), and thyroid cancer. We report here the efficacy, safety, and long-term results of single-agent...
7.
Siefker-Radtke A, Matsubara N, Park S, Huddart R, Burgess E, Ozguroglu M, et al.
Ann Oncol . 2023 Oct; 35(1):107-117. PMID: 37871702
Background: Erdafitinib is an oral pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor approved to treat locally advanced/metastatic urothelial carcinoma (mUC) in patients with susceptible FGFR3/2 alterations (FGFRalt) who progressed...
8.
Catto J, Tran B, Roupret M, Gschwend J, Loriot Y, Nishiyama H, et al.
Ann Oncol . 2023 Oct; 35(1):98-106. PMID: 37871701
Background: Treatment options are limited for patients with high-risk non-muscle-invasive bladder cancer (NMIBC) with disease recurrence after bacillus Calmette-Guérin (BCG) treatment and who are ineligible for/refuse radical cystectomy. FGFR alterations...
9.
Rosenberg J, Powles T, Sonpavde G, Loriot Y, Duran I, Lee J, et al.
Ann Oncol . 2023 Sep; 34(11):1047-1054. PMID: 37678672
Introduction: This exploratory analysis evaluated efficacy and safety data for enfortumab vedotin versus chemotherapy over a median follow-up of ∼2 years from EV-301. Materials And Methods: Patients with locally advanced/metastatic...
10.
Valery M, Saleh K, Ecea R, Michot J, Ribrag V, Fizazi K, et al.
Cancer Chemother Pharmacol . 2023 Jun; 92(3):229-233. PMID: 37354233
Background: Cytokine release syndrome (CRS) is a common adverse event of CAR T cell or bispecific antibody (bsAb) therapy. Anti-IL6/IL6R drugs are used in the management of auto-immune diseases. Some...