Y Koezuka
Overview
Explore the profile of Y Koezuka including associated specialties, affiliations and a list of published articles.
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77
Citations
5204
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Recent Articles
1.
Morita M, Sawa E, Yamaji K, Sakai T, Natori T, Koezuka Y, et al.
Biosci Biotechnol Biochem
. 2016 Jun;
60(2):288-92.
PMID: 27299402
A practical total synthesis of (2S,3S,4R)-l-O-(α-d-galactopyranosyl)-N-hexacosanoyl-2-amino-l,3,4-octadecanetriol (KRN7000), an antitumorial and immunostimulatory glycosphingolipid derived from agelasphins, was achieved in 14 steps starting from d-lyxose in a 16% overall yield.
2.
Saito A, Motomura N, Kakimi K, Narui K, Noguchi N, Sasatsu M, et al.
J Thorac Cardiovasc Surg
. 2008 Jul;
136(1):159-67.
PMID: 18603069
Objective: Surgical results have shown the superiority of human heart valve and vascular allografts over artificial prostheses when used for the treatment of infectious cardiovascular diseases. However, the mechanism of...
3.
Singh A, Wilson M, Hong S, Olivares-Villagomez D, Du C, Stanic A, et al.
J Exp Med
. 2001 Dec;
194(12):1801-11.
PMID: 11748281
Experimental autoimmune encephalomyelitis (EAE) serves as a prototypic model for T cell-mediated autoimmunity. V(alpha)14 natural killer T (NKT) cells are a subset of T lymphocytes that recognize glycolipid antigens presented...
4.
Jahng A, Maricic I, Pedersen B, Burdin N, Naidenko O, Kronenberg M, et al.
J Exp Med
. 2001 Dec;
194(12):1789-99.
PMID: 11748280
Natural killer (NK) T cells recognize lipid antigens in the context of the major histocompatibility complex (MHC) class 1-like molecule CD1 and rapidly secrete large amounts of the cytokines interferon...
5.
Naumov Y, Bahjat K, Gausling R, Abraham R, Exley M, Koezuka Y, et al.
Proc Natl Acad Sci U S A
. 2001 Nov;
98(24):13838-43.
PMID: 11707602
CD1d-restricted invariant NKT (iNKT) cells are immunoregulatory cells whose loss exacerbates diabetes in nonobese diabetic (NOD) female mice. Here, we show that the relative numbers of iNKT cells from the...
6.
Chiodoni C, Stoppacciaro A, Sangaletti S, Gri G, Cappetti B, Koezuka Y, et al.
Eur J Immunol
. 2001 Oct;
31(10):3101-10.
PMID: 11592087
The glycolipid alpha-galactosylceramide (alpha-GalCer), ligand of NKT cells, has been recently shown to induce antitumor immunity in mice through the induction of IL-12 production by dendritic cells. In the present...
7.
Tahir S, Cheng O, Shaulov A, Koezuka Y, Bubley G, Wilson S, et al.
J Immunol
. 2001 Sep;
167(7):4046-50.
PMID: 11564825
Invariant NK T cells express certain NK cell receptors and an invariant TCRalpha chain specific for the MHC class I-like CD1d protein. These invariant NK T cells can regulate diverse...
8.
Sharif S, Arreaza G, Zucker P, Mi Q, Sondhi J, Naidenko O, et al.
Nat Med
. 2001 Sep;
7(9):1057-62.
PMID: 11533711
Type 1 diabetes (T1D) in non-obese diabetic (NOD) mice may be favored by immune dysregulation leading to the hyporesponsiveness of regulatory T cells and activation of effector T-helper type 1...
9.
Hong S, Wilson M, Serizawa I, Wu L, Singh N, Naidenko O, et al.
Nat Med
. 2001 Sep;
7(9):1052-6.
PMID: 11533710
Diabetes in non-obese diabetic (NOD) mice is mediated by pathogenic T-helper type 1 (Th1) cells that arise because of a deficiency in regulatory or suppressor T cells. V alpha 14-J...
10.
Kikuchi A, Nieda M, Schmidt C, Koezuka Y, Ishihara S, Ishikawa Y, et al.
Br J Cancer
. 2001 Sep;
85(5):741-6.
PMID: 11531261
alpha-galactosylceramide (KRN 7000, alpha-GalCer) has shown potent in vivo anti-tumour activity in mice, including against melanoma and the highly specific effect of inducing proliferation and activation of human Valpha24+NKT-cells. We...