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Xun-Cheng Su

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Articles 95
Citations 1184
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Recent Articles
1.
Chen J, Chen S, Liu H, Pan B, Zhao Y, Fu X, et al.
J Am Chem Soc . 2025 Mar; PMID: 40064860
Due to their exceptional anisotropic magnetic properties, lanthanide ion (Ln) complexes are of great utility in many fields of chemistry, including magnetic materials, biomedical imaging, and nuclear magnetic resonance (NMR)...
2.
Wu Q, Yang X, Wang Y, Qin H, Su X, Xuan W
Angew Chem Int Ed Engl . 2025 Mar; :e202500983. PMID: 40035449
Isoaspartate (isoAsp) is a β-linked residue in proteins spontaneously generated through Asn deamidation or Asp dehydration and significantly affects protein properties. However, the sluggish and site-nonselective generation of isoAsp residues...
3.
Zhao L, Huang Z, Meng H, Liang Q, Su X, Xuan W
Bioconjug Chem . 2025 Feb; PMID: 39963974
Aldehyde represents an extremely useful bio-orthogonal group in chemical biology and has promoted the generation of high-quality bioconjugates in therapeutics development. However, the installation of an aldehyde group on a...
4.
Li Z, Xue Y, Duan Y, Yuan W, Chen C, Shi S, et al.
Int J Biol Macromol . 2025 Feb; 304(Pt 1):140791. PMID: 39924025
The death domain (DD) superfamily, a group of protein interaction modules, plays a crucial role in regulating downstream signaling pathways through the formation of specific complexes. However, the aggregation-prone behavior...
5.
Meng W, Zhang X, Pan B, Tan X, Zhao J, Liu Y, et al.
J Am Chem Soc . 2024 Dec; 147(1):234-246. PMID: 39731614
Pulsed dipolar electron paramagnetic resonance (PD-EPR) measurement is a powerful technique for characterizing the interactions and conformational changes of biomolecules. The extraction of these distance restraints from PD-EPR experiments relies...
6.
Guo S, Pan B, Li X, Xiao Y, Su X
Chem Commun (Camb) . 2024 Dec; 61(6):1156-1159. PMID: 39691950
Pseudocontact shift (PCS) contains rich structural information of proteins in structural and chemical biology. F-PCS is determined in live mammalian cells dual labelling of the target protein with a paramagnetic...
7.
Bogdanov A, Gao L, Dalaloyan A, Zhu W, Seal M, Su X, et al.
Phys Chem Chem Phys . 2024 Oct; 26(42):26921-26932. PMID: 39417349
F electron-nuclear double resonance (ENDOR) has emerged as an attractive method for determining distance distributions in biomolecules in the range of 0.7-2 nm, which is not easily accessible by pulsed...
8.
Yang X, Su X, Xuan W
Chembiochem . 2024 Jun; 25(17):e202400393. PMID: 38831474
Photocaged amino acids could be genetically encoded into proteins via genetic code expansion (GCE) and constitute unique tools for innovative protein engineering. There are a number of photocaged proteinogenic amino...
9.
Ben-Ishay Y, Barak Y, Feintuch A, Ouari O, Pierro A, Mileo E, et al.
Protein Sci . 2024 Feb; 33(3):e4903. PMID: 38358137
The combined effects of the cellular environment on proteins led to the definition of a fifth level of protein structural organization termed quinary structure. To explore the implication of potential...
10.
Guo S, Xiao Y, Pan B, Su X
Chembiochem . 2024 Jan; 25(4):e202300798. PMID: 38169080
Site-specific modification of proteins with synthetic fluorescent tag effectively improves the resolution of imaging, and such a labeling method with negligible three-dimensional structural perturbations and minimal impact on the biological...