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Xuenian Huang

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Articles 26
Citations 177
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Recent Articles
1.
Zhang Q, Wei X, Fang W, Huang X, Zhang X
Commun Biol . 2024 Sep; 7(1):1220. PMID: 39349686
The interplay between the insect immune system and entomopathogenic fungi during cuticle penetration is not yet fully understood. Here, we show that a secretory protein COA1 (coat of appressorium 1)...
2.
Geng C, Jin Z, Gu M, Li J, Tang S, Guo Q, et al.
Metab Eng . 2023 Jun; 78:183-191. PMID: 37315711
Trans-aconitic acid (TAA) is a promising bio-based chemical with the structure of unsaturated tricarboxylic acid, and also has the potential to be a non-toxic nematicide as a potent inhibitor of...
3.
Ding S, Chen J, Huang X, Zheng C, Sun T, Wu Z, et al.
Quant Imaging Med Surg . 2023 May; 13(5):3357-3364. PMID: 37179953
No abstract available.
4.
Men P, Zhou Y, Xie L, Zhang X, Zhang W, Huang X, et al.
Microb Cell Fact . 2023 Mar; 22(1):44. PMID: 36879280
Background: Micafungin is an echinocandin-type antifungal agent used for the clinical treatment of invasive fungal infections. It is semisynthesized from the sulfonated lipohexapeptide FR901379, a nonribosomal peptide produced by the...
5.
Hu M, Zhou Y, Du S, Zhang X, Tang S, Yang Y, et al.
Front Bioeng Biotechnol . 2023 Feb; 10:1093402. PMID: 36760750
Lysergic acid (LA) is the key precursor of ergot alkaloids, and its derivatives have been used extensively for the treatment of neurological disorders. However, the poor fermentation efficiency limited its...
6.
Zhang W, Zhang X, Feng D, Liang Y, Wu Z, Du S, et al.
Angew Chem Int Ed Engl . 2023 Jan; 62(12):e202215529. PMID: 36704842
Flavonoids are important plant natural products with variable structures and bioactivities. All known plant flavonoids are generated under the catalysis of a type III polyketide synthase (PKS) followed by a...
7.
Men P, Geng C, Zhang X, Zhang W, Xie L, Feng D, et al.
Metab Eng . 2022 Nov; 74:160-167. PMID: 36328296
Micafungin, a semisynthetic derivative of the cyclic hexapeptide FR901379 produced by Coleophoma empetri fermentation, is the only O-sulfonated echinocandin-type antifungal drug. However, the detailed formation mechanism of O-sulfonate group, whether...
8.
Qi F, Zhang W, Xue Y, Geng C, Jin Z, Li J, et al.
Metab Eng . 2022 Nov; 74:130-138. PMID: 36328293
Physcion is a characteristic component of the traditional herb rhubarb with diverse pharmacological activities that has been commercially approved as an herbal fungicide. Nevertheless, its extremely low contents, costly purification...
9.
Li H, Zhang W, Zhang X, Tang S, Men P, Xiong M, et al.
Mar Drugs . 2022 Aug; 20(8). PMID: 36005526
Filamentous fungi are abundant resources of bioactive natural products. Here, 151 marine-derived fungi were collected from the north Yellow Sea and identified by an internal transcribed spacer (ITS) sequence. The...
10.
Xue Y, Liang Y, Zhang W, Geng C, Feng D, Huang X, et al.
J Agric Food Chem . 2022 Apr; 70(18):5728-5737. PMID: 35475366
All -methylated derivatives of emodin, including physcion, questin, and 1--methylemodin, show potential antifungal activities. Notably, emodin and questin are two pivotal intermediates of geodin biosynthesis in . Although most of...