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Xue-Qun Chen

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Articles 37
Citations 336
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Recent Articles
11.
Chen X, Zhao Y, Du J
Sheng Li Ke Xue Jin Zhan . 2014 Jan; 44(5):323-8. PMID: 24475717
No abstract available.
12.
Zhao Y, Ren J, Wang M, Zhang S, Liu Y, Li M, et al.
Proc Natl Acad Sci U S A . 2013 Dec; 110(51):20639-44. PMID: 24297887
Mutational changes in p53 correlate well with tumorigenesis. Remarkably, however, relatively little is known about the role that p53 variations may play in environmental adaptation. Here we report that codon...
13.
14.
Yuan Y, Kong F, Hao K, Meng F, Chen X, Du J
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2013 Aug; 29(3):202-4, 208. PMID: 23940947
No abstract available.
15.
Wang M, Zhao Y, Zhang S, Chen X, Du J
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2013 Jul; 29(2):136-8. PMID: 23833967
No abstract available.
16.
Chen X, Kong F, Zhao Y, Du J
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2013 Apr; 28(6):481-7. PMID: 23581176
High-altitude hypoxia can induce physiological dysfunction and mountain sickness, but the underlying mechanism is not fully understood. Corticotrophin-releasing factor (CRF) and CRF type-i receptors (CRFR1) are members of the CRF...
17.
Zhao Y, Wang M, Hao K, Chen X, Du J
Peptides . 2013 Mar; 44:8-14. PMID: 23538210
We have previously reported that hypoxia activates corticotrophin-releasing hormone (CRH) and the expression of its type-1 receptor (CRHR1) and induces disorders of the brain-endocrine-immune network. p53 is activated by hypoxia...
18.
Wang X, Meng F, Liu Z, Fan J, Hao K, Chen X, et al.
Mol Neurobiol . 2013 Mar; 48(3):544-55. PMID: 23529784
Stress during gestation increases vulnerability to disease and changes behavior in offspring. We previously reported that hypoxia and restraint during pregnancy sensitized the hypothalamic-pituitary-adrenal (HPA) axis and induced anxiety-like behavior...
19.
Fan J, Wang X, Hao K, Yuan Y, Chen X, Du J
Horm Behav . 2012 Nov; 63(1):25-31. PMID: 23164543
We previously reported that gestational intermittent hypoxia (GIH) causes anxiety-like behavior in neonatal rats. Here, we showed that the anxiogenic effect was correlated with upregulation of corticotropin-releasing hormone receptor 1...
20.
Wang P, Kong F, Chen X, Du J
Zhejiang Da Xue Xue Bao Yi Xue Ban . 2011 Oct; 40(5):559-66. PMID: 21984162
HIF-1 is composed of HIF-1α and HIF-1β subunits. It promotes target genes transcription under hypoxia and plays essential roles in cell development, physiological adaptations, and pathological processes. In the past...