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Xue-Chun Yang

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Articles 13
Citations 19
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Recent Articles
1.
Yang X, Wu F, Wu W, Zhang X, Feng J
Chem Sci . 2024 Nov; 15(46):19488-19495. PMID: 39568897
Although cycloadditions of bicyclobutanes (BCBs) have emerged as a reliable approach for producing bicyclo[.1.1]alkanes such as azabicyclo[3.1.1]heptanes (aza-BCHeps), serving as saturated bioisosteres of arenes, the catalytic asymmetric variant remains underdeveloped...
2.
Wu W, Xu B, Yang X, Wu F, He H, Zhang X, et al.
Nat Commun . 2024 Sep; 15(1):8005. PMID: 39266575
The absence of catalytic asymmetric methods for synthesizing chiral (hetero)bicyclo[n.1.1]alkanes has hindered their application in new drug discovery. Here we demonstrate the achievability of an asymmetric polar cycloaddition of bicyclo[1.1.0]butane...
3.
Wu F, Wu W, Xiao Y, Li Z, Tang L, He H, et al.
Angew Chem Int Ed Engl . 2024 Sep; 63(48):e202406548. PMID: 39218783
The cycloaddition reaction involving bicyclo[1.1.0]butanes (BCBs) offers a versatile and efficient synthetic platform for producing C(sp)-rich rigid bridged ring scaffolds, which act as phenyl bioisosteres. However, there is a scarcity...
4.
Li R, Yang X, Wang Y, Li T, Zhang X, Gao O, et al.
Huan Jing Ke Xue . 2024 Aug; 45(8):4967-4979. PMID: 39168712
Petroleum pollution has become a prominent global environmental problem, restricting the coordinated development of the economy and the ecological environment. Although bioremediation has the advantages of low carbon, high efficiency,...
5.
Zhou J, Xiao Y, He L, Gao X, Yang X, Wu W, et al.
J Am Chem Soc . 2024 May; 146(29):19621-19628. PMID: 38739092
For nearly 60 years, significant research efforts have been focused on developing strategies for the cycloaddition of bicyclobutanes (BCBs). However, higher-order cycloaddition and catalytic asymmetric cycloaddition of BCBs have been...
6.
Yang X, Zhao J
Gels . 2024 Feb; 10(2). PMID: 38391430
Photocatalysis is one of the effective ways to degrade pollutant antibiotics. Agar is used as the adsorption module to provide abundant pore structure. Carbon dots (CDs) are selected as light...
7.
Tang C, Zhang Z, Sun Y, Ding W, Yang X, Song Y, et al.
Heliyon . 2023 Nov; 9(11):e21011. PMID: 37920504
Aging is associated with gradual changes in liver structure, altered metabolites and other physiological/pathological functions in hepatic cells. However, its characterized phenotypes based on altered metabolites and the underlying biological...
8.
Ding W, Li X, Tang C, Yang X, Sun Y, Song Y, et al.
Mol Cell Proteomics . 2023 Jan; 22(2):100494. PMID: 36621768
AMP-activated protein kinase alpha 2 (AMPKα2) regulates energy metabolism, protein synthesis, and glucolipid metabolism myocardial cells. Ketone bodies produced by fatty acid β-oxidation, especially β-hydroxybutyrate, are fatty energy-supplying substances for...
9.
Ling M, Yang X, Yu N, Song Y, Zheng Y, Tang C, et al.
Arch Biochem Biophys . 2022 Nov; 731:109430. PMID: 36326546
Diabetic cardiovascular complication is a common systemic disease with high morbidity and mortality worldwide. We hypothesise that exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs-exos) can rescue these...
10.
Yang X, Gao S, Fu S, Yao X, Jiao Z, Zhao J, et al.
Gels . 2022 Jul; 8(8). PMID: 35892718
Both sodium alginate and polyethyleneimine (PEI) have a good ability to adsorb heavy metal ions. PEI and sodium alginate were used as important precursors to synthesize positively charged carbon nanoparticles...