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Xizheng Zhang

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Recent Articles
21.
Yan Y, Sun H, Gong Y, Yan Z, Zhang X, Guo Y, et al.
Int J Mol Med . 2016 Jun; 38(2):594-600. PMID: 27314666
As integrins are mechanoresponsive, there exists an intimate relationship between integrins and mechanical strain. Integrin-β1 mediates the impact of mechanical strain on bone. Mechanical strain induces bone formation through the...
22.
Li D, Zhang Z, Zheng C, Zhao B, Sun K, Nian Z, et al.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi . 2016 Jun; 30(3):292-7. PMID: 27281872
Objective: To study the preparation and cytocompatibility of bone tissue engineering scaffolds by combining low temperature three dimensional (3D) printing and vacuum freeze-drying techniques. Methods: Collagen (COL) and silk fibroin...
23.
Guo Y, Wang Y, Liu Y, Wang H, Guo C, Zhang X
Chin J Traumatol . 2015 Dec; 18(3):150-6. PMID: 26643241
Purpose: To investigate the influence of the same mechanical loading on osteogenesis and osteoclastogenesis in vitro. Methods: Primary osteoblasts, bone marrow-derived mesenchymal stem cells (BMSCs, cultured in osteoinductive medium) and...
24.
Wang Y, Zou X, Guo Y, Wang L, Liu Y, Zeng Q, et al.
Cell Mol Biol Lett . 2015 Jul; 20(4):586-96. PMID: 26208382
MicroRNAs (miRNAs) are important regulators of cell proliferation, differentiation and function. Mechanical strain is an essential factor for osteoblast proliferation and differentiation. A previous study revealed that a physiological mechanical...
25.
Zeng Q, Guo Y, Liu Y, Li R, Zhang X, Liu L, et al.
Biol Res . 2015 May; 48:25. PMID: 25971622
Background: Mechanical strain plays a great role in growth and differentiation of osteoblast. A previous study indicated that integrin-β (β1, β5) mediated osteoblast proliferation promoted by mechanical tensile strain. However,...
26.
Guo Y, Wang Y, Liu Y, Liu Y, Zeng Q, Zhao Y, et al.
Mol Med Rep . 2015 May; 12(2):3033-8. PMID: 25937096
MicroRNA (miRNA) is an important regulator of cell differentiation and function. Mechanical strain is important in the growth and differentiation of osteoblasts. Therefore, mechanresponsive miRNA may be important in the...
27.
Guo Y, Zeng Q, Yan Y, Shen L, Liu L, Li R, et al.
Springerplus . 2013 Jul; 2(1):303. PMID: 23888274
Different cell/tissue derived extracellular matrix (ECM) display subtle differences that might provide important cues for proliferation and differentiation of cells in vitro or in vivo. However, the bioactivities of different...
28.
Li J, Wan Z, Liu H, Li H, Liu L, Li R, et al.
Ann Biomed Eng . 2013 Apr; 41(10):2056-66. PMID: 23609024
Bone remodeling is strictly mediated by the coupled activities of osteoblasts and osteoclasts, which are responsible for bone formation and resorption, respectively. Although many papers have been published on the...
29.
Sun D, Junger W, Yuan C, Zhang W, Bao Y, Qin D, et al.
Stem Cells . 2013 Feb; 31(6):1170-80. PMID: 23404811
Shockwave treatment promotes bone healing of nonunion fractures. In this study, we investigated whether this effect could be due to adenosine 5'-triphosphate (ATP) release-induced differentiation of human mesenchymal stem cells...
30.
Liu L, Guo Y, Chen X, Li R, Li Z, Wang L, et al.
Acta Biochim Biophys Sin (Shanghai) . 2012 Jun; 44(8):669-77. PMID: 22728916
Pre-osteoblast MC3T3-E1 cells were cultured in hyaluronic acid-modified chitosan/collagen/nano-hydroxyapatite (HA-CS/Col/nHAP) composite scaffolds and treated with phytoestrogen α-zearalanol (α-ZAL) to improve bone tissue formation for bone tissue engineering. Perfusion and dynamic...