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Xiuchun Cindy Tian

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Citations 430
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Recent Articles
1.
Liu Z, Cui J, Wang W, Li M, Wang Z, Presicce G, et al.
Zygote . 2022 Sep; 30(6):903-909. PMID: 36106584
Somatic cell nuclear transfer (NT) is associated with aberrant changes in epigenetic reprogramming that impede the development of embryos, particularly during zygotic genome activation. Here, we characterized epigenetic patterns of...
2.
Johnson E, Duan J, Srirattana K, Venkitanarayanan K, Tulman E, Tian X
Sci Rep . 2022 Apr; 12(1):5937. PMID: 35396364
With increasing antibiotic resistance, the use of plant derived antimicrobials (PDAs) has gained momentum. Here, we investigated the toxicity of trans-cinnamaldehyde, eugenol, and carvacrol after intramuscular injection in mice. Two...
3.
Su Y, Wang L, Fan Z, Liu Y, Zhu J, Kaback D, et al.
Int J Mol Sci . 2021 Oct; 22(19). PMID: 34638830
Pluripotent stem cells (PSCs) have been successfully developed in many species. However, the establishment of bovine-induced pluripotent stem cells (biPSCs) has been challenging. Here we report the generation of biPSCs...
4.
Sang L, Xiao Y, Jiang Z, Forde N, Tian X, Lonergan P, et al.
Mol Reprod Dev . 2021 Oct; 88(10):694-704. PMID: 34596291
Regulation of the mammalian embryo involves cell-signaling molecules produced by the maternal oviduct and endometrium. Here, datasets on the transcriptome of the gestational Days 5 and 6 bovine morula and...
5.
Duan J, Jiang Z, Alqahtani F, Mandoiu I, Dong H, Zheng X, et al.
Front Genet . 2019 Jun; 10:512. PMID: 31191619
DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis. The dynamics of global DNA methylation in bovine embryos, however, have mostly been studied by immunostaining. We adopted the whole genome...
6.
Duan J, Shi W, Jue N, Jiang Z, Kuo L, ONeill R, et al.
Genome Biol Evol . 2018 Dec; 11(1):242-252. PMID: 30566637
Dosage compensation of the mammalian X chromosome (X) was proposed by Susumu Ohno as a mechanism wherein the inactivation of one X in females would lead to doubling the expression...
7.
Duan J, Flock K, Jue N, Zhang M, Jones A, Al Seesi S, et al.
G3 (Bethesda) . 2018 Nov; 9(1):305-314. PMID: 30482800
Ohno's hypothesis predicts that the expression of the single X chromosome in males needs compensatory upregulation to balance its dosage with that of the diploid autosomes. Additionally, X chromosome inactivation...
8.
Duan J, Zhang M, Flock K, Al Seesi S, Mandoiu I, Jones A, et al.
Epigenetics . 2018 Jul; 13(8):793-807. PMID: 30051747
Genomic imprinting is an epigenetic phenomenon of differential allelic expression based on parental origin. To date, 263 imprinted genes have been identified among all investigated mammalian species. However, only 21...
9.
Jiang Z, Lin J, Dong H, Zheng X, Marjani S, Duan J, et al.
Biol Reprod . 2018 Jun; 99(5):949-959. PMID: 29912291
DNA methylation is an important epigenetic modification that undergoes dynamic changes in mammalian embryogenesis, during which both parental genomes are reprogrammed. Despite the many immunostaining studies that have assessed global...
10.
Wang L, Jiang Z, Huang D, Duan J, Huang C, Sullivan S, et al.
BMC Genomics . 2018 Mar; 19(1):183. PMID: 29510661
Background: The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is...