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Xiong-Wei Deng

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Articles 5
Citations 82
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Recent Articles
1.
Hu H, Deng X, Li R, Chen D, Xue C
Arch Med Sci . 2019 Jul; 15(4):1028-1034. PMID: 31360197
Introduction: For some cancers bone is the preferred site for metastasis and involves a cascade involving transition of epithelial cells to mesenchymal cells and subsequent intravasation to the blood and...
2.
Zhu Y, Zhou X, Zhu L, Yao C, Fang J, Zhou F, et al.
Oncotarget . 2016 Jul; 7(31):49527-49538. PMID: 27385099
In the present study, we investigated the activity of XL388, a novel mammalian target of rapamycin (mTOR) complex 1/2 (mTORC1/2) dual inhibitor, in preclinical osteosarcoma (OS) models. XL388 was cytotoxic,...
3.
Zhu Y, Min H, Fang J, Zhou F, Deng X, Zhang Y
Cancer Biol Ther . 2015 Apr; 16(4):602-9. PMID: 25869769
Recent studies have identified that constitutively active phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling is an important feature of osteosarcoma, where it promotes cell proliferation, survival, and chemo-resistance. Here,...
4.
Zhu Y, Xu Y, Fang J, Zhou F, Deng X, Zhang Y
Biochem Biophys Res Commun . 2014 Jul; 451(1):112-8. PMID: 25068992
The search for novel and more efficient chemo-agents against malignant osteoblastoma is important. In this study, we examined the potential anti-osteoblastoma function of bufotalin, and studied the underlying mechanisms. Our...
5.
Deng X, Min Z, Lin B, Zhang F
Chin J Traumatol . 2010 Jul; 13(4):229-33. PMID: 20670580
Objective: To investigate the feasibility of posterior fixation with 3.5-mm pedicle screws in the atlantoaxial vertebrae of children. Methods: In this study, atlantoaxial vertebrae specimens were obtained from 10 cadavers...