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Xiong-Jun Wang

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Articles 4
Citations 113
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Recent Articles
1.
Jing X, Wang X, Zhang T, Zhu W, Fang Y, Wu H, et al.
Cancer Res . 2019 Jun; 79(18):4650-4664. PMID: 31253668
Nucleotide supply is essential for DNA replication in proliferating cells, including cancer cells. Ribose-phosphate diphosphokinase 1 (PRPS1) is a key enzyme to produce the consensus precursor of nucleotide synthesis. PRPS1...
2.
Shao J, Lu J, Zhu W, Yu H, Jing X, Wang Y, et al.
Cell Death Differ . 2019 Feb; 26(11):2237-2252. PMID: 30728460
TP53 is the most frequently mutated gene in human cancer, whereas tumors with wild-type TP53 develop alternative strategies to survive. Identifying new regulators of p53 reactivation would greatly contribute to...
3.
Wang X, Qiao Y, Xiao M, Wang L, Chen J, Lv W, et al.
Cell Rep . 2017 Jan; 18(4):933-946. PMID: 28122243
LIF promotes self-renewal of mouse embryonic stem cells (mESCs), and in its absence, the cells differentiate. LIF binds to the LIF receptor (LIFR) and activates the JAK-STAT3 pathway, but it...
4.
Ma L, Huang C, Wang X, Xin D, Wang L, Zou Q, et al.
Mol Cell . 2017 Jan; 65(2):296-309. PMID: 28065600
In mammalian cells, histone deacetylase (HDAC) and Sirtuin (SIRT) are two families responsible for removing acetyl groups from acetylated proteins. Here, we describe protein deacetylation coupled with deacetylimination as a...