Xinbin Gu
Overview
Explore the profile of Xinbin Gu including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
459
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0
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Recent Articles
1.
Yang C, Pang X, Teng S, Wilson S, Gu X, Xie G
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859304
MEK inhibitors, such as trametinib, have shown therapeutic potential in head and neck squamous cell carcinoma (HNSCC). However, the factors influencing cancer cell sensitivity and resistance to MEK inhibition remain...
2.
Lan M, Niu E, Liu M, Anderson S, Barham L, Greenfield T, et al.
Dent Res Oral Health
. 2024 Apr;
7(1):36-42.
PMID: 38646068
Oral health plays a crucial role in overall well-being. One of the goals set by the US Department of Health and Human Service, Healthy People 2030 is to reducing dental...
3.
Sobitan A, Gebremedhin B, Yao Q, Xie G, Gu X, Li J, et al.
JCO Clin Cancer Inform
. 2024 Jan;
8:e2300140.
PMID: 38295322
Purpose: Thyroid peroxidase (TPO) is essential for the synthesis of thyroid hormones. However, specific mutations render TPO antigenic and prone to autoimmune attacks leading to thyroid cancer, TPO deficiency, and...
4.
Xie G, Shan L, Yang C, Liu Y, Pang X, Teng S, et al.
Sci Rep
. 2023 Oct;
13(1):18476.
PMID: 37898690
The innate immune stimulator of interferon genes (STING) pathway is known to activate type I interferons (IFN-I) and participate in generating antitumor immunity. We previously produced hDT806, a recombinant diphtheria...
5.
Cherry-Peppers G, Fryer C, Jackson A, Gu X, Ford D, Glascoe A, et al.
J Natl Med Assoc
. 2023 Jul;
116(6):636-641.
PMID: 37495445
Sickle Cell Disease (SCD) is genetically described as an autosomal blood disorder resulting from the presence of a mutated form of hemoglobin. Morbidity, frequency of crisis, degree of anemia, and...
6.
Chung J, Mustapha I, Li J, Gu X
Public Health Pract (Oxf)
. 2022 Sep;
3:100239.
PMID: 36101754
Objectives: Public understanding of human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) is minimally understood. Therefore uncovering communication gaps between the public and healthcare professionals regarding this disease is vital. Social media...
7.
Liu M, Kao D, Gu X, Holland W, Cherry-Peppers G
Int J Environ Res Public Health
. 2022 May;
19(9).
PMID: 35564382
Previous studies on individual-level variables have improved our knowledge base of oral health service use. However, environmental or contextual variables are also important in understanding oral health disparities in racial...
8.
Xie G, Shan L, Liu Y, Wu T, Gu X
Biology (Basel)
. 2022 Apr;
11(4).
PMID: 35453686
Over 90% of head and neck squamous cell carcinoma (HNSCC) overexpresses the epidermal growth factor receptor (EGFR). However, the EGFR-targeted monotherapy response rate only achieves 10-30% in HNSCC. Recombinant immunotoxin...
9.
Xie G, Zhu A, Gu X
Cancers (Basel)
. 2022 Apr;
14(7).
PMID: 35406486
Hepatocellular carcinoma (HCC) is a lethal malignancy with high mortality. The inhibition of cyclin-dependent kinase 7 (CDK7) activity has shown therapeutic efficacy in HCC. However, the underlying molecular mechanisms remain...
10.
Davis J, Liu M, Kao D, Gu X, Cherry-Peppers G
AMA J Ethics
. 2022 Feb;
24(1):E41-47.
PMID: 35133727
Background: Access to dental care in mixed-race and predominantly African American wards in the District of Columbia (DC) was investigated in relation to community development. Methods: This study used high-resolution...