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Xin-Yuan Shi

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Citations 68
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Recent Articles
1.
Xu B, Shi X, Luo G, Lin Z, Sun F, Dai S, et al.
Zhongguo Zhong Yao Za Zhi . 2020 Apr; 45(2):221-232. PMID: 32237303
Along with the striding of the Chinese medicine(CM) manufacturing toward the Industry 4.0, some digital factories have accumulated lightweight industrial big data, which become part of the enterprise assets. These...
2.
Dai S, Xu B, Shi X, Xu X, Sun Y, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1095-1103. PMID: 29027422
This study is aimed to propose a continual improvement strategy based on quality by design (QbD). An ultra high performance liquid chromatography (UPLC) method was developed to accomplish the method...
3.
Lin Z, Yang C, Xu B, Shi X, Zhang Z, Fu J, et al.
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1089-1094. PMID: 29027421
Blending process, which is an essential part of the pharmaceutical preparation, has a direct influence on the homogeneity and stability of solid dosage forms. With the official release of Guidance...
4.
Cui X, Xu B, Liu J, Shi G, Shi X, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1055-1061. PMID: 29027416
Raw materials' quality variation could affect the quality consistency of product and the clinical efficacy. In this paper, the high shear wet granulation (HSWG) process of the ginkgo leaf tablet...
5.
Cui X, Xu B, Sun F, Dai S, Shi X, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1048-1054. PMID: 29027415
In this paper, under the guidance of quality by design (QbD) concept, the control strategy of the high shear wet granulation process of the ginkgo leaf tablet based on the...
6.
Xu B, Cui X, Yang C, Wang X, Shi X, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1043-1047. PMID: 29027414
Quality by design (QbD) highlights the concept of "begin with the end", which means to thoroughly understand the target product quality first, and then guide pharmaceutical process development and quality...
7.
Cui X, Xu B, Zhang Y, Zhang N, Shi X, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1037-1042. PMID: 29027413
In this paper, the granules intermediate prepared from the wet granulation process of ginkgo leaf tablet were taken as the research object, and then the stackability, homogeneity, flowability, compressibility and...
8.
Xu B, Shi X, Wu Z, Zhang Y, Wang Y, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Oct; 42(6):1015-1024. PMID: 29027410
The pharmaceutical quality was built by design, formed in the manufacturing process and improved during the product's lifecycle. Based on the comprehensive literature review of pharmaceutical quality by design (QbD),...
9.
Du C, Wu Z, Zhao N, Zhou Z, Shi X, Qiao Y
Zhongguo Zhong Yao Za Zhi . 2017 Sep; 41(19):3563-3568. PMID: 28925149
To establish a rapid quantitative analysis method for online monitoring of chlorogenic acid in aqueous solution of Lonicera Japonica Flos extraction by using micro-electromechanical near infrared spectroscopy (MEMS-NIR). High performance...
10.
Yang C, Xu B, Zhang Z, Wang X, Shi X, Fu J, et al.
Zhongguo Zhong Yao Za Zhi . 2017 Sep; 41(19):3557-3562. PMID: 28925148
Blending uniformity is essential to ensure the homogeneity of Chinese medicine formula particles within each batch. This study was based on the blending process of ebony spray dried powder and...