Xin-Xing Gu
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Explore the profile of Xin-Xing Gu including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
430
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Recent Articles
1.
Damron F, Barbier M, Dubey P, Edwards K, Gu X, Klein N, et al.
J Immunol
. 2020 Aug;
205(4):877-882.
PMID: 32769142
Despite high vaccine coverage in many parts of the world, pertussis is resurging in a number of areas in which acellular vaccines are the primary vaccine administered to infants and...
2.
Gu X, Plotkin S, Edwards K, Sette A, Mills K, Levy O, et al.
Clin Vaccine Immunol
. 2017 May;
24(7).
PMID: 28490424
Since the middle of the 20th century, vaccines have made a significant public health impact by controlling infectious diseases globally. Although long-term protection has been achieved with some vaccines, immunity...
3.
Lee L, Gu X, Nahm M
Vaccines (Basel)
. 2015 Sep;
2(1):112-28.
PMID: 26344470
Seven-valent pneumococcal conjugate vaccine (PCV7) introduction and routine pediatric use has substantially reduced the burden of Streptococcus pneumoniae disease worldwide. However, a significant amount of disease burden, due to serotypes...
4.
Gao S, Ren D, Peng D, Zhang W, Muszynski A, Carlson R, et al.
J Med Microbiol
. 2013 Mar;
62(Pt 6):807-812.
PMID: 23475908
Lipo-oligosaccharide (LOS) is a major surface component and virulence factor of the human respiratory pathogen Moraxella catarrhalis. Two late acyltransferase genes, lpxX and lpxL, have been identified involved in the...
5.
Hassan F, Ren D, Zhang W, Merkel T, Gu X
PLoS One
. 2012 Jun;
7(5):e37610.
PMID: 22662179
Moraxella catarrhalis is a gram negative bacterium and a leading causative agent of otitis media (OM) in children. Several recent reports have provided strong evidence for an association between toll...
6.
Hassan F, Ren D, Zhang W, Gu X
PLoS One
. 2012 Jun;
7(5):e37912.
PMID: 22655080
Moraxella catarrhalis is a gram negative bacterium and a leading causative agent of otitis media (OM) in children. Recent reports have provided strong evidence for the presence of high levels...
7.
Ren D, Nelson K, Uchakin P, Smith A, Gu X, Daines D
Exp Biol Med (Maywood)
. 2012 May;
237(5):540-7.
PMID: 22569032
Non-typeable Haemophilus influenzae (NTHi) are human-adapted Gram-negative bacteria that comprise part of the normal flora of the human upper airway, but are also responsible for a number of mucosal infections...
8.
Ren D, Xie H, Zhang W, Hassan F, Petralia R, Yu S, et al.
PLoS One
. 2012 Jan;
6(12):e29553.
PMID: 22216312
Background: There are no licensed vaccines available against Moraxella catarrhalis, a significant human respiratory pathogen. Lipooligosaccharide (LOS) based conjugate vaccines derived from individual serotype M. catarrhalis only showed partial protection...
9.
Ren D, Yu S, Gao S, Peng D, Petralia R, Muszynski A, et al.
Vaccine
. 2011 Apr;
29(25):4210-7.
PMID: 21501641
There is no licensed vaccine available against Moraxella catarrhalis, an exclusive human pathogen responsible for otitis media in children and respiratory infections in adults. We previously developed conjugate vaccine candidates...
10.
Hong W, Peng D, Rivera M, Gu X
Microbes Infect
. 2009 Sep;
12(1):11-8.
PMID: 19782149
Otitis media (OM) can occur following outset of upper respiratory tract infections. Inhibition of bacterial colonization in nasopharynx (NP) by mucosal vaccination may prevent OM by reducing bacterial invasion of...