Xin-Ping Zhao
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Explore the profile of Xin-Ping Zhao including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
267
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Recent Articles
1.
Chang S, Liao M, Miyata K, Pang Y, Zhao X, Peng J, et al.
Transl Res
. 2025 Jan;
277:13-26.
PMID: 39756674
Renal hedgehog interacting protein (Hhip) activates sodium-glucose cotransporter 2 (Sglt2) expression and promotes tubular senescence in murine diabetic kidney disease (DKD), yet its underlying mechanism(s) are poorly understood. Here we...
2.
Liao M, Lo C, Pang Y, Yang W, Su K, Zhao X, et al.
Transl Res
. 2024 Jan;
267:1-9.
PMID: 38195017
Heterogeneous nuclear ribonucleoprotein F (HnRNP F) is a key regulator for nucleic acid metabolism; however, whether HnRNP F expression is important in maintaining podocyte integrity is unclear. Nephroseq analysis from...
3.
Zhao X, Chang S, Pang Y, Liao M, Peng J, Ingelfinger J, et al.
Diabetologia
. 2022 Oct;
66(1):223-240.
PMID: 36260124
Aims/hypothesis: Senescent renal tubular cells may be linked to diabetic kidney disease (DKD)-related tubulopathy. We studied mice with or without diabetes in which hedgehog interacting protein (HHIP) was present or...
4.
Liao M, Miyata K, Chang S, Zhao X, Lo C, El-Mortada M, et al.
Clin Sci (Lond)
. 2022 May;
136(10):715-731.
PMID: 35502764
Podocyte damage and loss are the early event in the development of focal segmental glomerulosclerosis (FSGS). Podocytes express angiotensin II type-2-receptor (AT2R), which may play a key role in maintaining...
5.
Miyata K, Lo C, Zhao S, Zhao X, Chenier I, Yamashita M, et al.
Diabetologia
. 2021 Aug;
64(11):2589-2601.
PMID: 34370045
Aims/hypothesis: We previously reported that renal tubule-specific deletion of heterogeneous nuclear ribonucleoprotein F (Hnrnpf) results in upregulation of renal angiotensinogen (Agt) and downregulation of sodium-glucose co-transporter 2 (Sglt2) in Hnrnpf...
6.
Liao M, Pang Y, Chang S, Zhao X, Chenier I, Ingelfinger J, et al.
Diabetologia
. 2021 May;
64(9):2108-2121.
PMID: 34047808
Aims/hypothesis: The angiotensin II receptor type 2 (ATR) may be a potential therapeutic target for the treatment of hypertension and chronic kidney disease (CKD). The expression and function of ATR...
7.
Zhao S, Lo C, Miyata K, Ghosh A, Zhao X, Chenier I, et al.
Diabetes
. 2021 Apr;
70(6):1388-1403.
PMID: 33820760
We investigated the impact of nuclear factor erythroid 2-related factor 2 (Nrf2) overexpression in renal proximal tubular cells (RPTCs) on blood glucose, kidney injury, and sodium-glucose cotransporter 2 (Sglt2) expression...
8.
Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney disease
Miyata K, Zhao X, Chang S, Liao M, Lo C, Chenier I, et al.
Transl Res
. 2019 Dec;
217:1-10.
PMID: 31794697
Glomerular endothelial cell (GEC) dysfunction occurs in diabetic kidney disease (DKD) and generally precedes albuminuria. We recently reported that hedgehog interacting protein (Hhip), highly expressed in GECs, contributes to DKD...
9.
Nchienzia H, Liao M, Zhao X, Chang S, Lo C, Chenier I, et al.
Sci Rep
. 2019 Aug;
9(1):11183.
PMID: 31371780
Hedgehog interacting protein (Hhip) is essential for islet formation and beta-cell proliferation during pancreatic development; abnormally elevated Hhip expression has been linked to human pancreatitis. Here, we investigate the role...
10.
Zhao X, Chang S, Liao M, Lo C, Chenier I, Luo H, et al.
Sci Rep
. 2018 Apr;
8(1):5958.
PMID: 29654303
We investigated whether renal hedgehog interacting protein (Hhip) expression contributes to the progression of diabetic nephropathy (DN) and studied its related mechanism(s) in vivo and in vitro. Here, we show...