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Xilong Zhang

Explore the profile of Xilong Zhang including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 64
Citations 1120
Followers 0
Related Specialties
General Medicine
Pulmonary Medicine
Top 10 Co-Authors
Ning Ding
Mei Su
Mao Huang
Wenxiao Ding
Yanbin Dong
Hanpeng Huang
Jing Xu
Sutapa Mukherjee
Geraldo Lorenzi-Filho
Zili Meng
Published In
Sleep Breath
Zhonghua Yi Xue Za Zhi
Chin Med J (Engl)
PLoS One
Zhonghua Jie He He Hu Xi Za Zhi
Affiliations
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Recent Articles
21.
Depression of Non-Neuronal Cholinergic System May Play a Role in Co-Occurrence of Subjective Daytime Sleepiness and Hypertension in Patients with Obstructive Sleep Apnea Syndrome
Meng Z, Sun B, Chen W, Zhang X, Huang M, Xu J
Nat Sci Sleep . 2021 Dec; 13:2153-2163. PMID: 34934375
Purpose: Simultaneous occurrence of hypertension and excessive daytime sleepiness (EDS) is very common in obstructive sleep apnea syndrome (OSAS), although no study has specifically addressed this issue. The present study...
22.
Globular adiponectin protects hepatocytes against intermittent hypoxia-induced injury via Pink1/Parkin-mediated mitophagy induction
Ding W, Dong Y, Zhang X
Sleep Breath . 2021 Oct; 26(3):1389-1397. PMID: 34698981
Purpose: This study sought to determine the effect of Pink1/Parkin-mediated mitophagy on liver cells exposed to intermittent hypoxia (IH) and the roles of globular adiponectin (gAPN). Methods: The hepatocyte model...
23.
How Does Chronic Intermittent Hypoxia Influence Upper Airway Stability in Rats?
Meng Y, Li W, Zou Y, Yao Y, Huang H, Sun J, et al.
Nat Sci Sleep . 2020 Oct; 12:749-758. PMID: 33117010
Background: Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway collapse during sleep. The contraction of upper airway dilator muscles plays a crucial role in maintaining UA...
24.
The rate of decrease in oxygen desaturation during severe obstructive sleep apnea syndrome is correlated with subjective excessive daytime sleepiness
Zhang S, Meng Z, Zhang X, Huang M, Xu J
Sleep Breath . 2020 Oct; 25(3):1285-1291. PMID: 33099726
Purpose: To explore factors that influence subjective excessive daytime sleepiness (EDS) in patients with severe obstructive sleep apnea syndrome (OSAS). Methods: Patients with snoring seen at the Sleep Medicine Center...
25.
Globular adiponectin alleviates chronic intermittent hypoxia-induced H9C2 cardiomyocytes apoptosis via ER-phagy induction
Zhang Q, Zhang X, Ding N, Ge L, Dong Y, He C, et al.
Cell Cycle . 2020 Oct; 19(22):3140-3153. PMID: 33092434
This study evaluated the effects of endoplasmic reticulum autophagy (ER-phagy) and globular adiponectin (gAPN) on chronic intermittent hypoxia (CIH)-induced H9C2 cardiomyocytes injury while investigating potential mechanisms of action. The CIH...
26.
The role of mitophagy in the mechanism of genioglossal dysfunction caused by chronic intermittent hypoxia and the protective effect of adiponectin
Wang W, Ding W, Huang H, Zhu Y, Ding N, Feng G, et al.
Sleep Breath . 2020 Oct; 25(2):931-940. PMID: 33033994
Purpose: Dysfunction of the genioglossus muscle is important in the pathogenesis of obstructive sleep apnea due to chronic intermittent hypoxia (CIH). Mitochondrial impairment resulting from hypoxia is mitigated by mitophagy...
27.
Adiponectin ameliorates lung injury induced by intermittent hypoxia through inhibition of ROS-associated pulmonary cell apoptosis
Ding W, Zhang X, Zhang Q, Dong Y, Wang W, Ding N
Sleep Breath . 2020 May; 25(1):459-470. PMID: 32458376
Purpose: Obstructive sleep apnea hypopnea syndrome has been reported to be associated with pulmonary hypertension (PH). Adiponectin (Ad) has many protective roles in the human body, including its function as...
28.
Continuous Positive Airway Pressure Treatment, Glycemia, and Diabetes Risk in Obstructive Sleep Apnea and Comorbid Cardiovascular Disease
Loffler K, Heeley E, Freed R, Meng R, Bittencourt L, Gonzaga Carvalho C, et al.
Diabetes Care . 2020 Apr; 43(8):1859-1867. PMID: 32291275
Objective: Despite evidence of a relationship among obstructive sleep apnea (OSA), metabolic dysregulation, and diabetes, it is uncertain whether OSA treatment can improve metabolic parameters. We sought to determine effects...
29.
Oxygen desaturation rate as a novel intermittent hypoxemia parameter in severe obstructive sleep apnea is strongly associated with hypertension
Wang N, Meng Z, Ding N, Chen W, Zhang X, Huang M, et al.
J Clin Sleep Med . 2020 Feb; 16(7):1055-1062. PMID: 32105212
Study Objectives: To investigate the effects of different intermittent hypoxemia properties on blood pressure (BP) and short-term blood pressure variability (BPV) in severe obstructive sleep apnea (OSA) patients. Methods: Nocturnal...
30.
Predictors of long-term adherence to continuous positive airway pressure in patients with obstructive sleep apnea and cardiovascular disease
Van Ryswyk E, Anderson C, Antic N, Barbe F, Bittencourt L, Freed R, et al.
Sleep . 2019 Oct; 42(10). PMID: 31587046
Study Objectives: Poor adherence to continuous positive airway pressure (CPAP) commonly affects therapeutic response in obstructive sleep apnea (OSA). We aimed to determine predictors of adherence to CPAP among participants...