Xiaoyuan Dai Perrard
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Explore the profile of Xiaoyuan Dai Perrard including associated specialties, affiliations and a list of published articles.
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9
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580
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Recent Articles
1.
Antony A, Lian Z, Perrard X, Perrard J, Liu H, Cox A, et al.
Diabetes
. 2020 Dec;
70(3):720-732.
PMID: 33323395
CD11c macrophages/dendritic cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose tissue (AT) and may contribute to AT inflammation and insulin resistance. Stat1 is a...
2.
Lian Z, Saeed A, Peng X, Perrard X, Jia X, Hussain A, et al.
J Clin Lipidol
. 2020 Oct;
14(6):850-858.
PMID: 33011137
Background: Accumulation of lipoprotein X (LpX) in blood can cause severe hypercholesterolemia and cutaneous xanthomas. Monocytes sensitively sense lipid changes in circulation and contribute to inflammation. However, how monocytes respond...
3.
Xu L, Perrard X, Perrard J, Yang D, Xiao X, Teng B, et al.
Arterioscler Thromb Vasc Biol
. 2015 Jun;
35(8):1787-97.
PMID: 26112011
Objective: To examine infiltration of blood foamy monocytes, containing intracellular lipid droplets, into early atherosclerotic lesions and its contribution to development of nascent atherosclerosis. Approach And Results: In apoE(-/-) mice...
4.
Wooten J, Wu H, Raya J, Perrard X, Gaubatz J, Hoogeveen R
Cholesterol
. 2014 Mar;
2014:843468.
PMID: 24672716
Our current understanding of oxysterol metabolism during different disease states such as obesity and dyslipidemia is limited. Therefore, the aim of this study was to determine the effect of diet-induced...
5.
Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, et al.
Arterioscler Thromb Vasc Biol
. 2013 Oct;
34(1):34-43.
PMID: 24158516
Objective: T cells, particularly CD8(+) T cells, are major participants in obesity-linked adipose tissue (AT) inflammation. We examined the mechanisms of CD8(+) T-cell accumulation and activation in AT and the...
6.
Wang J, Perrard X, Perrard J, Mukherjee A, Rosales C, Chen Y, et al.
Atherosclerosis
. 2012 Jul;
223(2):342-9.
PMID: 22770993
Objective: To identify the role of triglyceride-rich lipoproteins (TGRLs) and apoE, a major apolipoprotein in TGRLs, in adipose tissue inflammation with high-fat diet (HFD)-induced obesity. Methods: Male apoE(-/-) and C57BL/6J...
7.
Wang Q, Perrard X, Perrard J, Mansoori A, Raya J, Hoogeveen R, et al.
Atherosclerosis
. 2011 Aug;
219(1):100-8.
PMID: 21824616
Objective: We studied the effects of weight loss induced by either a low-fat normal diet (ND) or restriction of high-fat diet (HFD) on hepatic steatosis, inflammation in the liver and...
8.
Wu H, Perrard X, Wang Q, Perrard J, Polsani V, Jones P, et al.
Arterioscler Thromb Vasc Biol
. 2009 Nov;
30(2):186-92.
PMID: 19910635
Objective: To examine CD11c, a beta(2)-integrin, on adipose tissue (AT) leukocytes and blood monocytes and its role in diet-induced obesity. Methods And Results: High-fat diet-induced obese C57BL/6 mice, CD11c-deficient mice,...
9.
Wu H, Ghosh S, Perrard X, Feng L, Garcia G, Perrard J, et al.
Circulation
. 2007 Feb;
115(8):1029-38.
PMID: 17296858
Background: Obesity is associated with chronic inflammation, which includes increased macrophage accumulation in adipose tissue (AT) and upregulation of chemokines and cytokines. T cells also play important roles in chronic...