Xiaoxiao Cai
Overview
Explore the profile of Xiaoxiao Cai including associated specialties, affiliations and a list of published articles.
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Articles
155
Citations
2063
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Recent Articles
1.
Yin W, Chen X, Bai L, Li Y, Chen W, Jiang Y, et al.
Biomaterials
. 2025 Feb;
319:123194.
PMID: 39970843
Bone Morphogenetic Protein-2 (BMP-2) is a key growth factor for inducing osteogenic differentiation and promoting bone remodeling. However, the exogenous application of delivery systems for BMP-2 has been hampered by...
2.
Zhou M, Lu Y, Tang Y, Zhang T, Xiao D, Zhang M, et al.
Biomaterials
. 2025 Feb;
318:123183.
PMID: 39951831
Targeted regulation of neutrophils is an effective approach for treating neutrophil-driven inflammatory diseases, but challenges remain in minimizing off-target effects and extending drug half-life. A DNA-based nanorobot was developed to...
3.
Du G, Yao Y, Chen W, Lin Y, He Y, Zhou M, et al.
ACS Appl Mater Interfaces
. 2025 Feb;
17(8):11925-11936.
PMID: 39939157
Acute ischemic stroke (AIS) is associated with a high mortality rate and poor prognosis, with a lack of effective therapeutic drugs for post-thrombolytic treatment. MicroRNA-based gene therapy is a promising...
4.
Han Q, Li J, Deng H, Shi S, Zhou M, Cai X, et al.
Small
. 2025 Jan;
e2411740.
PMID: 39828624
Diabetic periodontitis presents a unique therapeutic challenge, primarily due to its chronic inflammatory profile and the associated bone loss driven by immune dysregulation. Metformin (Met) is recognized for its potent...
5.
Zhou M, Tang Y, Lu Y, Zhang T, Zhang S, Cai X, et al.
ACS Nano
. 2025 Jan;
19(3):3455-3469.
PMID: 39817852
Targeted drug delivery is a promising strategy for treating inflammatory diseases, with recent research focusing on the combination of neutrophils and nanomaterials. In this study, a targeted nanodrug delivery platform...
6.
Zhang S, Chen T, Lu W, Lin Y, Zhou M, Cai X
Adv Sci (Weinh)
. 2024 Dec;
12(6):e2411261.
PMID: 39721013
Bacterial infections resistant to antimicrobial treatments, particularly those caused by Pseudomonas aeruginosa (P. aeruginosa), frequently lead to elevated mortality rates. Tackling this resistance using therapeutic combinations with varied mechanisms has...
7.
Li S, Zhao Y, Lyu X, Chen Y, Zhang T, Lin S, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(10):e2411210.
PMID: 39717886
MicroRNA (miRNA)-based therapy holds significant potential; however, its structural limitations pose a challenge to the full exploitation of its biomedical functionality. Framework nucleic acids are promising owing to their transportability,...
8.
Yue Z, Yang Y, Nie L, Sun Y, Wang Q, Lin Y, et al.
Small
. 2024 Dec;
:e2408323.
PMID: 39690794
Extensive accumulation of senescent cells contributes to organismal aging, and slowing down the process of cellular senescence may ameliorate age-related pathologies. Targeted inhibition of the mechanistic target of rapamycin complex...
9.
Cai Z, Bai L, Li Q, Li Y, Cai X, Lin Y
ACS Nano
. 2024 Dec;
18(52):35214-35229.
PMID: 39689347
Diabetic osteoporosis, a prevalent chronic complication of diabetes, is marked by reduced bone mass, increased bone fragility, and susceptibility to fractures. A significant cause of this condition is the disruption...
10.
Wu H, Lyu X, Xu M, Chen Y, Liao S, Zhang G, et al.
ACS Appl Mater Interfaces
. 2024 Dec;
17(1):560-571.
PMID: 39679863
Periodontitis is a chronic inflammatory disease that leads to periodontal tissue damage and tooth loss. Therefore, controlling inflammatory bone loss and promoting osteogenesis is a crucial challenge clinically. MicroRNA (miRNA)...