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Xiaohang Qian

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Articles 9
Citations 97
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Recent Articles
1.
Qian X, Hai W, Chen S, Zhang M, Jiang X, Tang H
Gut Microbes . 2023 Nov; 15(2):2282790. PMID: 37992400
Numerous studies have described the notable impact of gut microbiota on the brain in Alzheimer's disease (AD) via the gut - brain axis. However, the molecular mechanisms underlying the involvement...
2.
Zheng H, Qian X, Tian W, Cao L
Brain Sci . 2022 Jun; 12(6). PMID: 35741659
Parkinson's disease (PD) is the second most common neurodegenerative disorder, and the mechanism of its occurrence is still not fully elucidated. Accumulating evidence has suggested that the gut acts as...
3.
Liu X, Ke H, Qian X, Wang S, Zhan F, Li Z, et al.
J Neurol . 2022 Apr; 269(9):4717-4728. PMID: 35428900
Background: Mutations in PRRT2 and 16p11.2 microdeletion including PRRT2 have been identified as the pathogenic cause of paroxysmal kinesigenic dyskinesia (PKD). Objective: The objective was to investigate the clinical and...
4.
Song X, Zhu Z, Qian X, Liu X, Chen S, Tang H
Molecules . 2022 Mar; 27(6). PMID: 35335269
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder frequently accompanied by cognitive impairment. Contributing factors such as modern lifestyle, genetic predisposition, and gene environmental interactions have been postulated,...
5.
Qian X, Liu X, Zhu Z, Wang S, Song X, Chen G, et al.
Front Genet . 2021 Aug; 12:616761. PMID: 34354730
Occipital cortical malformation (OCCM) is a disease caused by malformations of cortical development characterized by polymicrogyria and pachygyria of the occipital lobes and childhood-onset seizures. The recessive or complex heterozygous...
6.
Jiang J, Chen G, Wu J, Luan X, Zhou H, Liu X, et al.
Front Genet . 2020 Jul; 11:682. PMID: 32714376
Background: Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disorder of bile acid synthesis caused by mutations in the CYP27A1 gene. CTX is an underdiagnosed and potentially treatable disease, thus a...
7.
Zhao P, Qian X, Nie Y, Sun N, Wang Z, Wu J, et al.
Front Behav Neurosci . 2019 Jul; 13:138. PMID: 31293402
Alzheimer's disease (AD) is a devastating disease in the elderly with no known effective treatment. It is characterized by progressive deterioration of memory and cognition. Many new potential targets are...
8.
Nie Y, Wang Z, Chai G, Xiong Y, Li B, Zhang H, et al.
Molecules . 2019 Apr; 24(8). PMID: 30999647
Acute lung injury (ALI) is a severe clinical disease marked by dysregulated inflammation response and has a high rate of morbidity and mortality. Macrophages, which play diverse roles in the...
9.
Nie Y, Zhang D, Jin Z, Li B, Wang X, Che H, et al.
Clin Exp Pharmacol Physiol . 2019 Mar; 46(6):575-586. PMID: 30854687
It has been established that lanatoside C, a FDA-approved cardiac glycoside, reduces proliferation of cancer cell lines. The proliferation of fibroblasts is critical to the pathogenesis of pulmonary fibrosis (PF),...